Piccioni Maria Grazia, Merlino Lucia, D'Ovidio Giulia, Del Prete Federica, Galli Valerio, Petrivelli Lucia, Vena Flaminia, D'Ambrosio Valentina, Giancotti Antonella, Brunelli Roberto
Department of Maternal, Infantile and Urological Sciences, University of Rome La Sapienza, Viale del Policlinico, 155, 00161 Rome, Italy.
J Clin Med. 2022 Nov 30;11(23):7127. doi: 10.3390/jcm11237127.
Perforation of the ileum in the antepartum period resulting in meconial peritonitis is a condition that, although rare, is burdened by several complications. In 80-90% of cases, meconial ileus is the first manifestation of a disease, cystic fibrosis. In the remaining 10-20% of cases, it is caused by other situations, such as prematurity. In most cases, the diagnosis of meconial ileus occurs after birth, although in some cases it can be suspected prenatally, with the finding of a hyperechoic intestine on second trimester ultrasound. The prognosis depends on the gestational age, the location of the obstruction and the presence of fetal abnormalities. Mortality is very high and the recovery of intestinal function in the postoperative course is very high risk. In this case series, we describe two meconial peritonitis and our experience at the center.
产前回肠穿孔导致胎粪性腹膜炎是一种虽罕见但伴有多种并发症的病症。在80% - 90%的病例中，胎粪性肠梗阻是一种疾病——囊性纤维化的首发表现。在其余10% - 20%的病例中，它由其他情况引起，如早产。在大多数情况下，胎粪性肠梗阻的诊断在出生后做出，尽管在某些情况下产前即可怀疑，表现为孕中期超声检查发现肠道回声增强。预后取决于孕周、梗阻部位以及胎儿有无异常。死亡率很高，术后肠道功能恢复面临极高风险。在本病例系列中，我们描述了两例胎粪性腹膜炎及我们中心的经验。
