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新身体指标在确定阻塞性睡眠呼吸暂停综合征患者心血管疾病风险中的作用

The Usefulness of New Body Indices in Determining the Risk of Cardiovascular Disease in Cases with Obstructive Sleep Apnea Syndrome.

作者信息

Yeşildağ Mihrican, Şentürk Zühal, Bekci Taha Tahir, Guney İbrahim

机构信息

Department of Chest Diseases S.B University Konya Training and Research Hospital, Konya, Turkey.

Department of Nephrology, S.B University Konya Training and Research Hospital, Konya, Turkey.

出版信息

Int J Gen Med. 2024 Nov 26;17:5523-5534. doi: 10.2147/IJGM.S489904. eCollection 2024.

Abstract

PURPOSE

Obstructive Sleep Apnea Syndrome (OSAS) is considered a notable independent risk factor for cardiometabolic disorders. The current study aimed to investigate the efficacy of new anthropometric indices, A Body Shape Index (ABSI) and the Body Roundness Index (BRI), in assessing cardiovascular risk (CVR) and cardiovascular disease (CVD) among OSAS patients and to compare them with traditional indices.

MATERIALS AND METHODS

The records of 281 patients who consulted our sleep center were retrospectively reviewed. Patients were categorized according to OSA severity using AHI values. They were also classified based on cardiovascular conditions (CVR and CVD). ABSI, BRI, and traditional indices [such as body mass index (BMI), neck circumference (NC)] of the patient groups were evaluated.

RESULTS

Of the 281 patients recruited, 218 (77.6%) were diagnosed with OSAS. The distribution of cardiovascular conditions among the OSAS patients was: CVD (20%), CVR (39.8%), and control (40.2%). The new index BRI (Odds ratio-OR: 2.641, 95% CI: 1.24-5.62) has shown better predictive ability for CVR compared to traditional measures, while NC (OR: 1.320, 95% CI: 1.09-1.60) was the only predictor of CVD. Additionally, the BRI had a higher AUC value (0.656) than traditional indices in terms of diagnostic performance in distinguishing CVR. Another new index ABSI was not found to be significant in evaluating cardiovascular conditions.

CONCLUSION

BRI, one of the new indices, is a useful anthropometric parameter in the CVR assessment of OSAS patients, offering better predictive ability than traditional measurements.

摘要

目的

阻塞性睡眠呼吸暂停综合征(OSAS)被认为是心脏代谢紊乱的一个显著独立危险因素。本研究旨在探讨新的人体测量指标,即体型指数(ABSI)和体圆度指数(BRI),在评估OSAS患者心血管风险(CVR)和心血管疾病(CVD)方面的有效性,并将它们与传统指标进行比较。

材料与方法

回顾性分析了281名到我们睡眠中心就诊患者的记录。根据呼吸暂停低通气指数(AHI)值对患者进行OSA严重程度分类。他们还根据心血管状况(CVR和CVD)进行了分类。评估了患者组的ABSI、BRI和传统指标[如体重指数(BMI)、颈围(NC)]。

结果

在招募的281名患者中,218名(77.6%)被诊断为OSAS。OSAS患者心血管状况的分布为:CVD(20%)、CVR(39.8%)和对照组(40.2%)。与传统测量方法相比,新指标BRI(优势比-OR:2.641,95%可信区间:1.24-5.62)对CVR显示出更好的预测能力,而NC(OR:1.320,95%可信区间:1.09-1.60)是CVD的唯一预测指标。此外,在区分CVR的诊断性能方面,BRI的曲线下面积(AUC)值(0.656)高于传统指标。另一个新指标ABSI在评估心血管状况方面未发现有显著意义。

结论

新指标之一的BRI是OSAS患者CVR评估中一个有用的人体测量参数,比传统测量方法具有更好的预测能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1451/11609410/b2455bfa52b9/IJGM-17-5523-g0001.jpg

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