中枢胆碱能神经元的神经营养因子在正常脑组织和阿尔茨海默病脑组织中均有存在。
Neurotrophic factor for central cholinergic neurones is present in both normal and Alzheimer brain tissue.
作者信息
Atterwill C K, Bowen D M
出版信息
Acta Neuropathol. 1986;69(3-4):341-2. doi: 10.1007/BF00688315.
PMID:3962611
Abstract
Reaggregate cultures of foetal rat brain grown in a serum-free medium were used to determine the presence or absence of cholinergic neurotrophic factors in Alzheimer's disease brain tissue. These preliminary data show that both normal and Alzheimer's disease brain contain factors which elevate choline acetyltransferase activity in the reaggregate cultures.
摘要
利用在无血清培养基中培养的胎鼠脑再聚集培养物来确定阿尔茨海默病脑组织中是否存在胆碱能神经营养因子。这些初步数据表明，正常脑组织和阿尔茨海默病脑组织中都含有能提高再聚集培养物中胆碱乙酰转移酶活性的因子。
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