Aminimoghaddam Soheila, Sarchami Niloufar, Ghaderi Elahe
Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Tehran, Iran.
Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Int J Surg Case Rep. 2025 Jan;126:110651. doi: 10.1016/j.ijscr.2024.110651. Epub 2024 Nov 26.
Placenta increta (PI) can mimic a rare malignant tumor called Placental-site trophoblastic tumor (PSTT) with similar laboratory and clinical findings. Histological findings can help correctly diagnose PI from rare malignant tumors of PSTT.
According to our knowledge, only one case of PI has been reported in the literature, each of which had different characteristics, and various aspects of this lesion still need to be clarified. We reported a case of PI mimicking PSTT in a 37-year-old female. The uniqueness of the present case was its huge size and no history of abortion compared to the PI reported in the previous study.
Our patients' ultrasound and immunohistochemical characteristics were similar to the case reported in the study. After the complete hysterectomy, the patient's bleeding stopped completely, and the patient remained disease-free during the two-year follow-up.
PI can mimic a rare malignant tumor called PSTT with similar laboratory and clinical findings (Severe bleeding). The differential diagnosis of retained placenta in patients with extensive bleeding, either after vaginal delivery or after Cesarean section or abortion, should be carefully considered from PSTT. Both diseases (PSTT and PI) are treated with hysterectomy. Histological findings can help correctly diagnose PI from rare malignant tumors of PSTT.
胎盘植入(PI)可表现出与一种罕见恶性肿瘤——胎盘部位滋养细胞肿瘤(PSTT)相似的实验室及临床特征。组织学检查结果有助于从PSTT这种罕见恶性肿瘤中正确诊断出PI。
据我们所知,文献中仅报道过一例PI,每例都有不同特点,且该病变的各个方面仍有待阐明。我们报告了一例37岁女性患者,其PI表现类似PSTT。与先前研究报道的PI相比,本病例的独特之处在于其体积巨大且无流产史。
我们患者的超声及免疫组化特征与该研究报道的病例相似。全子宫切除术后,患者出血完全停止,在两年随访期间无疾病复发。
PI可表现出与罕见恶性肿瘤PSTT相似的实验室及临床特征(严重出血)。对于阴道分娩、剖宫产或流产后出现大量出血的患者,鉴别诊断胎盘残留时应仔细考虑PSTT。两种疾病(PSTT和PI)均采用子宫切除术治疗。组织学检查结果有助于从PSTT这种罕见恶性肿瘤中正确诊断出PI。