Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Acadey of Medical Sciences, Beijing, People's Republic of China.
Eur J Obstet Gynecol Reprod Biol. 2019 Nov;242:109-113. doi: 10.1016/j.ejogrb.2019.09.014. Epub 2019 Sep 24.
To analyse the management of patients with placenta accreta spectrum (PAS) disorders who underwent 2 trimester pregnancy terminations.
The records of patients with PAS disorders who underwent 2 trimester pregnancy terminations were collected and analysed.
Twenty-eight patients were included; 8 (28.6%) patients received prenatal diagnoses and 20 (71.4%) patients received postnatal diagnoses. In the prenatal diagnosis group, scheduling hysterotomy and placenta removal were performed in 5 patients with complete placenta previa and previous caesarean delivery without hysterectomy or postpartum haemorrhage, and medical termination was performed in 3 patients, 2 of whom retained the placenta in situ. In the postnatal diagnosis group, the placenta remained in situ in 11 patients, and in 13 (46.4%) patients overall, adjuvant treatments were applied to the patients, and the abnormally implanted placenta was passed 43.5 (range: 7-102) days after termination. A complication associated with the placenta left in situ included intrauterine infection in one case. Uterus preservation was achieved in all the patients.
For patients with PAS disorders with complete placenta previa and previous caesarean delivery, hysterotomy is a safe choice for terminating a 2 trimester pregnancy. When it is impossible to manually remove the placenta, leaving the placenta in situ with the administration of adjuvant treatment is a good choice for uterus preservation.
分析 2 孕期终止妊娠并发胎盘植入谱系(PAS)疾病患者的管理方法。
收集并分析了 PAS 疾病患者 2 孕期终止妊娠的病例记录。
共纳入 28 例患者,8 例(28.6%)患者接受了产前诊断,20 例(71.4%)患者接受了产后诊断。在产前诊断组中,5 例完全性前置胎盘且既往无剖宫产史患者行剖宫产术和胎盘切除术,3 例患者行药物流产,其中 2 例胎盘原位保留。在产后诊断组中,11 例胎盘仍原位保留,13 例(46.4%)患者接受了辅助治疗,异常植入胎盘在终止妊娠后 43.5(范围:7-102)天排出。1 例胎盘原位保留的患者并发宫内感染。所有患者均保留了子宫。
对于完全性前置胎盘且既往有剖宫产史的 PAS 疾病患者,行剖宫产术终止 2 孕期妊娠是安全的选择。当无法手动去除胎盘时,辅以药物治疗保留胎盘是一种很好的保留子宫的选择。