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有氧运动和抗阻运动对2型糖尿病患者血糖的急性影响:系统评价与荟萃分析

Acute effect of aerobic and resistance exercise on glycemia in individuals with type 2 diabetes: Systematic review and meta-analysis.

作者信息

de Almeida Josiane Aparecida, Batalha Ana Paula Delgado Bomtempo, Santos Carolina Vargas de Oliveira, Fontoura Tamiris Schaeffer, Laterza Mateus Camaroti, da Silva Lilian Pinto

机构信息

Graduate Program in Rehabilitation Sciences and Physical-Functional Performance, Faculty of Physical Therapy, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.

Graduate Program in Physical Education, Faculty of Physical Education and Sport, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.

出版信息

Braz J Phys Ther. 2025 Jan-Feb;29(1):101146. doi: 10.1016/j.bjpt.2024.101146. Epub 2024 Dec 2.

DOI:10.1016/j.bjpt.2024.101146
PMID:39626547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11647603/
Abstract

BACKGROUND

Type 2 diabetes (T2D) is the most prevalent in the world population, and exercise is one of the main non-pharmacological interventions to treat this health condition.

OBJECTIVE

To evaluate the effect of a single session of aerobic exercise (AE) and/or resistance exercise (RE) on post-exercise glycemia in individuals with T2D.

METHODS

A literature search was conducted in CINAHL, Cochrane Library, EMBASE, Google Scholar, LILACS, MEDLINE/Ovid, SciELO, SPORTDiscus, and Web of Science up to May 2024, randomized and non-randomized clinical trials were included. The risk of bias and the certainty of evidence were assessed using the Cochrane "Risk of Bias" and GRADE tools, respectively.

RESULTS

Initially, 7210 studies were identified, 26 were included in the systematic review, and 13 in the meta-analysis. A single session of continuous AE (CAE), interval AE (IAE), or RE promoted a significant reduction in glycemia in the first minute after exercise (-1.48 mmol/L [95 % CI:-1.73, -1.23]; -2.66 mmol/L [95 % CI:-3.48, -1.84]; -1.18 mmol/L [95 % CI:-2.15, -0.21], respectively), compared to the control session. This reduction persisted for up to 10 min after the CAE session (-1.61 mmol/L [95 % CI:-2.21, -1.01]) and up to 30 min after the IAE session (-1.11 mmol/L [95 % CI:-1.88, -0.35]). The risk of bias was assessed as uncertain, and the quality of the evidence was moderate.

CONCLUSION

CAE and IAE reduces glycemia for a period of up to 10 or 30 min after its completion, respectively, while a single session of RE reduces glycemia only in the first-minute post-exercise in individuals with T2D.

摘要

背景

2型糖尿病(T2D)在世界人口中最为普遍,运动是治疗这种健康状况的主要非药物干预措施之一。

目的

评估单次有氧运动(AE)和/或抗阻运动(RE)对T2D患者运动后血糖的影响。

方法

截至2024年5月,在CINAHL、Cochrane图书馆、EMBASE、谷歌学术、LILACS、MEDLINE/Ovid、SciELO、SPORTDiscus和科学网进行了文献检索,纳入随机和非随机临床试验。分别使用Cochrane“偏倚风险”和GRADE工具评估偏倚风险和证据的确定性。

结果

最初确定了7210项研究,26项纳入系统评价,13项纳入荟萃分析。与对照组相比,单次连续有氧运动(CAE)、间歇有氧运动(IAE)或抗阻运动(RE)在运动后第一分钟显著降低血糖(分别为-1.48 mmol/L [95%CI:-1.73,-1.23];-2.66 mmol/L [95%CI:-3.48,-1.84];-1.18 mmol/L [95%CI:-2.15,-0.21])。CAE运动后这种降低持续长达10分钟(-1.61 mmol/L [95%CI:-2.21,-1.01]),IAE运动后持续长达30分钟(-1.11 mmol/L [95%CI:-1.88,-0.35])。偏倚风险评估为不确定,证据质量为中等。

结论

CAE和IAE分别在运动结束后长达10分钟或30分钟的时间内降低血糖,而单次RE仅在T2D患者运动后的第一分钟降低血糖。

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Unsupervised Anomaly Detection to Characterize Heterogeneity in Type 2 Diabetes.无监督异常检测用于表征2型糖尿病的异质性。
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