2型糖尿病患者对单关节和多关节抗阻运动的急性血糖和血流动力学反应：一项随机交叉试验的初步研究

Acute Glycemic and Hemodynamic Responses to Single- and Multi-Joint Resistance Exercises in Individuals with Type 2 Diabetes: A Pilot Randomized Crossover Study.

作者信息

Delevatti Rodrigo Sudatti, da Silva Fábio Duarte, Braga Filipe De Lucca, Pfeifer Lucineia Orsolin, Sirydakis Maria Eduarda de Moraes

机构信息

Grupo de Pesquisa em Exercício Clínico (GPEC), Centro de Desportos, Universidade Federal de Santa Catarina, R. Deputado Antônio Edu Vieira, Pantanal, Florianópolis 88040-001, Brazil.

Faculdade de Motricidade Humana, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.

出版信息

Int J Environ Res Public Health. 2025 Aug 18;22(8):1288. doi: 10.3390/ijerph22081288.

DOI:10.3390/ijerph22081288

PMID:40869873

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12386599/

Abstract

INTRODUCTION

There is a lack of knowledge regarding the acute glycemic and blood pressure responses to resistance exercises that involve different amounts of muscle mass.

OBJECTIVE

To analyze the acute effects of single- and multi-joint resistance exercises on glycemic control and blood pressure in individuals with type 2 diabetes (T2DM).

METHODS

This is a pilot randomized crossover trial, including adults with T2DM of both genders. The participants performed three sessions (two experimental sessions: one with single-joint exercises (SIN) and the other with multi-joint exercises (MULTI); and a control session (CON)) in a randomized order, with outcomes being evaluated pre-exercise, immediately, 15 and 30 min after the sessions. Both sessions consisted of five exercises performed in three sets of 10 to 12 maximum repetitions. Analyses were performed by generalized estimation equations.

RESULTS

Fifteen adults (including eleven women) participated in this study. Both experimental sessions showed glycemic reductions immediately after the sessions (MULTI: -17 mg/dL; SIN: -29 mg/dL; < 0.001), and these values were kept similar up to 30 min after the session. The control session presented a glycemic reduction immediately after the session (-18 mg/dL), which increased 15 min later (-29 mg/dL), stabilizing up to 30 min after the session. Systolic blood pressure was increased immediately after both experimental sessions, retuning to baseline values 15 min post-session. Diastolic blood pressure increased in the control session with time, without any alterations in the experimental sessions.

CONCLUSIONS

Similar glycemic reductions were found in the experimental sessions, without superiority over the control session. Minimal changes were found in blood pressure.

摘要

引言

对于涉及不同肌肉量的抗阻运动的急性血糖和血压反应，人们了解不足。

目的

分析单关节和多关节抗阻运动对2型糖尿病（T2DM）患者血糖控制和血压的急性影响。

方法

这是一项试点随机交叉试验，纳入了成年男女T2DM患者。参与者按随机顺序进行三个阶段（两个试验阶段：一个进行单关节运动（SIN），另一个进行多关节运动（MULTI）；以及一个对照阶段（CON）），在运动前、运动后即刻、运动后15分钟和30分钟评估结果。两个试验阶段均包括五项运动，每组进行三组，每组10至12次最大重复次数。采用广义估计方程进行分析。

结果

15名成年人（包括11名女性）参与了本研究。两个试验阶段在运动后即刻均出现血糖降低（MULTI：-17mg/dL；SIN：-29mg/dL；P<0.001），这些值在运动后30分钟内保持相似。对照阶段在运动后即刻出现血糖降低（-18mg/dL），15分钟后升高（-29mg/dL），在运动后30分钟内保持稳定。两个试验阶段后即刻收缩压均升高，运动后15分钟恢复至基线值。对照阶段舒张压随时间升高，试验阶段无任何变化。