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丹麦的瑞氏综合征。一项回顾性研究。

Reye's syndrome in Denmark. A retrospective study.

作者信息

Daugbjerg P, Ranek L

出版信息

Acta Paediatr Scand. 1986 Mar;75(2):313-5. doi: 10.1111/j.1651-2227.1986.tb10205.x.

DOI:10.1111/j.1651-2227.1986.tb10205.x
PMID:3962663
Abstract

We tried to determine the incidence of Reye's syndrome (RS) in Denmark in a retrospective study. As RS is often preceded by influenza B, we chose the year 1979, where an epidemic of influenza B was registered in Denmark. All children aged 1 month to 18 years, who died, were identified, excluding children who died from accidents or malignant diseases. Two hundred and forty-two children died in hospital. Review of the records revealed one case of RS. One hundred and five died outside hospital. Reviewing death certificates and autopsy reports, none of these fulfilled the criteria for RS. All paediatric departments were asked if they had made a diagnosis of RS. None had. In 1979 approximately 1.1 mill. children aged 1 month to 14 years lived in Denmark. This gives an incidence of 0.09 per 100 000 for 1979. Although this is a minimum figure, the incidence of RS in Denmark, for unknown reasons, seems very low.

摘要

我们通过一项回顾性研究来试图确定丹麦雷氏综合征(RS)的发病率。由于RS常常在乙型流感之后出现,我们选择了1979年,这一年丹麦登记了乙型流感疫情。确定了所有1个月至18岁死亡儿童的信息,但排除死于意外事故或恶性疾病的儿童。242名儿童在医院死亡。查阅记录发现1例RS。105名儿童在院外死亡。查阅死亡证明和尸检报告,这些儿童均不符合RS的诊断标准。我们询问了所有儿科部门是否诊断出RS,结果均无诊断出该疾病的情况。1979年丹麦约有110万1个月至14岁的儿童。由此得出1979年的发病率为每10万人中0.09例。尽管这是一个最低数字,但丹麦RS的发病率出于未知原因似乎非常低。

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