Györffy-Wagner Z, Englund E, Larsson E M, Brun A, Cronqvist S, Persson B
Acta Radiol Diagn (Stockh). 1986 Jan-Feb;27(1):115-8. doi: 10.1177/028418518602700123.
In order to establish the validity of in vitro determination of the proton magnetic resonance (MR) relaxation times T1 and T2 in brain tissue at increasing time delay after death or operative excision, 81 brain tissue samples from 23 pigs were analyzed repeatedly. These samples, representing cortex, caudate nucleus and white matter, were studied microscopically after MR measurements. The T1 values exhibited no time dependence and the T2 values decreased slightly during the interval 2 to 90 hours after death. The samples were stored at +8 degrees C between the measurements. These results indicate that reliable in vitro measurements can be obtained in autopsy or surgical brain tissue specimens within 90 hours after death or excision, if handled properly.
为了确定死后或手术切除后随时间延迟增加，脑组织中质子磁共振（MR）弛豫时间T1和T2的体外测定的有效性，对来自23头猪的81个脑组织样本进行了反复分析。这些代表皮质、尾状核和白质的样本在进行MR测量后进行了显微镜检查。T1值未显示出时间依赖性，而T2值在死后2至90小时的时间段内略有下降。测量期间样本保存在8摄氏度。这些结果表明，如果处理得当，在死后或切除后90小时内的尸检或手术脑组织标本中可以获得可靠的体外测量结果。
