Reinert Camile, Gabiatti Mariana Papini, Pillmann-Ramos Hanna, Silva Diego Augusto Santos, de Fragas Hinnig Patrícia, de Carvalho Jolmerson, Panza Vilma Simões Pereira, da Silva Edson Luiz, Hansen Fernanda
Graduate Student in Nutrition, Department of Nutrition, Health Sciences Center, Federal University of Santa Catarina, University Campus, Trindade, Florianópolis, Santa Catarina, 88040-900, Brazil.
Undergraduate Student in Pharmaceutical Sciences, Department of Clinical Analyses, Health Sciences Center, Federal University of Santa Catarina, University Campus, Trindade, Florianópolis, Santa Catarina, 88040-900, Brazil.
Sci Rep. 2024 Dec 3;14(1):30121. doi: 10.1038/s41598-024-80963-5.
Background Dietary antioxidant Capacity (DaC) has been used as a tool for predicting plasma and dietary antioxidant concentrations. However, the DaC association with oxidative stress (OS) and body composition parameters is an unexplored area, mainly in physically active individuals. Given the potential for increased OS in physically active individuals, it becomes crucial to investigate this association. The aim of this study was to analyze the association between DaC, OS biomarkers, and body composition in healthy and physically active individuals. Methods This Cross-sectional study included 20 male soccer referees. Body composition measurements (body mass, fat mass, lean mass, and waist circumference), OS biomarkers (F2-isoprostane, total antioxidant state, total oxidative status, reduced glutathione, oxidized glutathione, superoxide dismutase, glutathione peroxidase (GPx) and catalase), and DaC were evaluated. Linear regression models were used to determine the association between DaC and the dependent variables. The study was approved by the Human Research Ethics Committee of the Federal University of Santa Catarina (UFSC), CAAE 82584318.0.0000.0121, and file no. 2.572.301. Results DaC was inversely associated with F2-isoprostane (p = 0.044), GPx activity (p = 0.048), and body fat percentage (p = 0.025). Conclusions Increased DaC in physically active individuals may bring benefits related to biomarkers of OS, such as decreasing F2-isoprostane and increasing GPx activity. The increase in DaC also showed an improvement in body composition, demonstrated by the lower percentage of body fat in the study subjects.
背景 膳食抗氧化能力（DaC）已被用作预测血浆和膳食抗氧化剂浓度的工具。然而，DaC与氧化应激（OS）和身体成分参数之间的关联是一个未被探索的领域，主要是在身体活跃的个体中。鉴于身体活跃个体中OS增加的可能性，研究这种关联变得至关重要。本研究的目的是分析健康且身体活跃的个体中DaC、OS生物标志物和身体成分之间的关联。方法 这项横断面研究纳入了20名男性足球裁判。评估了身体成分测量指标（体重、脂肪量、瘦体重和腰围）、OS生物标志物（F2-异前列腺素、总抗氧化状态、总氧化状态、还原型谷胱甘肽、氧化型谷胱甘肽、超氧化物歧化酶、谷胱甘肽过氧化物酶（GPx）和过氧化氢酶）以及DaC。使用线性回归模型来确定DaC与因变量之间的关联。该研究获得了圣卡塔琳娜联邦大学（UFSC）人类研究伦理委员会的批准，批准号为CAAE 82584318.0.0000.0121，文件编号为2.572.301。结果 DaC与F2-异前列腺素（p = 0.044）、GPx活性（p = 0.048）和体脂百分比（p = 0.025）呈负相关。结论 身体活跃个体中DaC的增加可能带来与OS生物标志物相关的益处，如降低F2-异前列腺素和增加GPx活性。DaC的增加还显示出身体成分的改善，研究对象的体脂百分比降低证明了这一点。
