Baykemagn Fitiwi Tinsae, Abreha Girmatsion Fisseha, Zelelow Yibrah Berhe, Kahsay Alemayehu Bayray
College of Medicine and Health Sciences, Adigrat University, Tigray, Ethiopia.
School of Public Health, College of Health Sciences, Mekelle University, Tigray, Ethiopia.
Sci Rep. 2024 Dec 3;14(1):30022. doi: 10.1038/s41598-024-81415-w.
Globally, potentially life-threatening maternal conditions (PLTCs) are significant public health threats. Ethiopia had the highest prevalence of PLTC (17.55%). However, there is limited evidence on the determinants that increase the occurrence of PLTC in Ethiopia. Therefore, this study aimed to identify determinants of the PLTC in Tigray, northern Ethiopia. A case‒control study was carried out between January 21 and April 20, 2024. Data were collected from 1027 participants (341 cases and 686 controls) through interviews and card reviews. Bivariate and multivariate logistic regression analyses were performed via SPSS version 24 to identify factors associated with the PLTC. In this study, variables such as having no formal education (AOR: 2.78; 95% CI 1.50-5.15), not in a marital union (AOR: 4.33; 95% CI 1.23-15.23), alcohol intake during pregnancy (AOR: 1.77; 95% CI 1.13-2.76), a history of stillbirth (AOR: 3.02; 95% CI 1.81-5.04), twin birth (AOR: 2.24; 95% CI 1.03-4.86), chronic hypertension (AOR: 11.37; 95% CI 3.71-34.88), prior cesarean section (CS) (AOR: 2.40; 95% CI 1.27-4.50), malaria during pregnancy (AOR: 4.10; 95% CI 1.25-13.45), not taking foliate (AOR: 4.10; 95% CI 1.25-13.45), induced labor (AOR: 7.33; 95% CI 4.31-12.47), and CS delivery (AOR: 2.39; 1.59-3.6) were increased risk of PLTC. However, completing recommended prenatal care visits (AOR: 0.59; 95% CI 0.41-0.86) was associated with lower odds of developing PLTC. Therefore, governmental and nongovernmental organizations, programmers, and healthcare providers should use the underlying evidence for the prevention and management of the PLTC.
在全球范围内，潜在危及生命的孕产妇疾病（PLTCs）是重大的公共卫生威胁。埃塞俄比亚的PLTC患病率最高（17.55%）。然而，关于埃塞俄比亚增加PLTC发生的决定因素的证据有限。因此，本研究旨在确定埃塞俄比亚北部提格雷地区PLTC的决定因素。2024年1月21日至4月20日进行了一项病例对照研究。通过访谈和病历审查从1027名参与者（341例病例和686名对照）中收集数据。使用SPSS 24版进行双变量和多变量逻辑回归分析，以确定与PLTC相关的因素。在本研究中，诸如未接受正规教育（调整后比值比[AOR]：2.78；95%置信区间[CI] 1.50 - 5.15）、未处于婚姻关系中（AOR：4.33；95% CI 1.23 - 15.23）、孕期饮酒（AOR：1.77；95% CI 1.13 - 2.76）、死产史（AOR：3.02；95% CI 1.81 - 5.04）、双胞胎分娩（AOR：2.24；95% CI 1.03 - 4.86）、慢性高血压（AOR：11.37；95% CI 3.71 - 34.88）、既往剖宫产（CS）（AOR：2.40；95% CI 1.27 - 4.50）、孕期疟疾（AOR：4.10；95% CI 1.25 - 13.45）、未服用叶酸（AOR：4.10；95% CI 1.25 - 13.45）、引产（AOR：7.33；95% CI 4.31 - 12.47）和剖宫产分娩（AOR：2.39；1.59 - 3.6）等变量会增加PLTC的风险。然而，完成推荐的产前检查（AOR：0.59；95% CI 0.41 - 0.86）与发生PLTC的较低几率相关。因此，政府和非政府组织、规划者以及医疗保健提供者应利用这些潜在证据来预防和管理PLTC。
