Webb Howard, Morcom Samuel
MBBS, ENT Registrar, Otolaryngology and Head and Neck Surgery, Austin Hospital, Melbourne, Vic.
FRACS, ENT Surgeon, Otolaryngology and Head and Neck Surgery, Austin Hospital, Melbourne, Vic.
Aust J Gen Pract. 2024 Dec;53(12):928-931. doi: 10.31128/AJGP-11-23-7032.
Chronic rhinosinusitis (CRS) is a very common reason for presentation to a general practitioner. It can be very difficult to manage and can have a significant effect on the quality of life of patients.
The objective of this article is to provide an up-to-date review of the pathophysiology, diagnosis and multimodal approach to management of this chronic condition.
Biologic agents are becoming increasingly common in Australia for the management of CRS with polyposis. This review includes an overview of these biologic agents and highlights their indications, efficacy and place in the management of CRS.
慢性鼻-鼻窦炎（CRS）是患者就诊于全科医生的常见原因。其治疗可能非常困难，并且会对患者的生活质量产生重大影响。
本文旨在对这种慢性病的病理生理学、诊断及多模式治疗方法进行最新综述。
在澳大利亚，生物制剂在伴有鼻息肉的CRS治疗中越来越普遍。本综述概述了这些生物制剂，并重点介绍了它们在CRS治疗中的适应证、疗效及地位。
