一种有潜力养活全世界并让人类在太空生活的化学酶级联反应。
A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space.
作者信息
Wu Shuke, Bornscheuer Uwe T
机构信息
State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, University Greifswald, D-17487 Greifswald, Germany.
出版信息
Eng Microbiol. 2021 Nov 3;2(1):100006. doi: 10.1016/j.engmic.2021.100006. eCollection 2022 Mar.
While the typical targets of (chemo-)enzymatic cascades are fine chemicals (e.g., pharmaceuticals), a chemoenzymatic cascade, artificial starch anabolic pathway (ASAP), was recently developed to synthesize starch from CO. The key results and outstanding features of ASAP are discussed here. We envision that ASAP and its microbial counterpart may enable efficient synthesis of food and sequestration of CO in a circular manner, thus contributing to a sustainable and hunger-free world and future habitation in space.
虽然（化学）酶级联反应的典型目标是精细化学品（如药物），但最近开发了一种化学酶级联反应——人工淀粉合成途径（ASAP），用于从CO合成淀粉。本文讨论了ASAP的关键成果和突出特点。我们设想，ASAP及其微生物对应物可能实现以循环方式高效合成食物和封存CO，从而为可持续和无饥饿的世界以及未来的太空居住做出贡献。
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