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印度近距离放射治疗协会关于乳腺癌近距离放射治疗的共识建议。

Indian Brachytherapy Society consensus recommendations for brachytherapy in breast cancer.

作者信息

Sharma Daya Nand, Budrukkar Ashwini, Kumar Rishabh, Wadasadawala Tabassum, Sarin Rajiv, Upreti Rituraj, Binjola Ashish, Mahantshetty Umesh, Badwe Rajendra

机构信息

Department of Radiation Oncology, AIIMS, New Delhi, India.

Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, India.

出版信息

J Contemp Brachytherapy. 2024 Aug;16(4):257-267. doi: 10.5114/jcb.2024.142936. Epub 2024 Sep 12.

Abstract

PURPOSE

This consensus statement of Indian Brachytherapy Society (IBS) aims to generate practical and reproducible guidelines allowing for direct implementation in the Indian scenario.

MATERIAL AND METHODS

IBS board of directors appointed a panel of physicians with expertise in breast cancer and, in particular, breast brachytherapy, to develop a consensus statement. First, a literature review on breast brachytherapy was conducted, focusing on randomized trials, prospective studies, and multi-institutional series. Then, guidelines were drafted based on authors' consensus according to Indian scenario.

RESULTS

IBS advocate accelerated partial breast irradiation (APBI) with brachytherapy following breast conservation surgery (BCS) for suitable groups of patients. Also, IBS recommends brachytherapy as the preferred technique for patients requiring tumor bed boost. Multi-catheter interstitial brachytherapy (MIB) is suitable in most situations, except for a large tumor to breast ratio, and type 2 oncoplasty or higher performed. For best cosmesis, IBS recommends a minimum 3-week gap between chemotherapy and APBI.

CONCLUSIONS

Brachytherapy continues to be an established technique for APBI as well as boost in appropriately selected patients with early breast cancer (EBC). As breast brachytherapy is an underutilized therapy in the Indian context, this article will hopefully encourage the readers to use its clinical potential in the suitable groups of patients.

摘要

目的

印度近距离放射治疗协会(IBS)的这份共识声明旨在制定切实可行且可重复的指南,以便能在印度的实际情况中直接实施。

材料与方法

IBS董事会任命了一个由乳腺癌尤其是乳腺近距离放射治疗领域的专家组成的医生小组,以制定一份共识声明。首先,对乳腺近距离放射治疗进行了文献综述,重点关注随机试验、前瞻性研究和多机构系列研究。然后,根据作者们基于印度实际情况达成的共识起草了指南。

结果

IBS主张对合适的患者群体在保乳手术(BCS)后采用近距离放射治疗进行加速部分乳腺照射(APBI)。此外,IBS推荐将近距离放射治疗作为需要对瘤床进行加量照射的患者的首选技术。多导管组织间近距离放射治疗(MIB)在大多数情况下都适用,但肿瘤与乳房比例较大以及进行了2型或更高类型乳房整形手术的情况除外。为了获得最佳美容效果,IBS建议化疗与APBI之间至少间隔3周。

结论

近距离放射治疗仍然是对适当选择的早期乳腺癌(EBC)患者进行APBI以及加量照射的成熟技术。鉴于在印度,乳腺近距离放射治疗是一种未得到充分利用的治疗方法,本文有望鼓励读者在合适的患者群体中发挥其临床潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9a/11609857/b2e2c030d8f8/JCB-16-54750-g001.jpg

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