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拔管决策:儿科重症监护病房中临床医生的判断与客观拔管准备标准之间的关联

The Decision to Extubate: The Association between Clinician Impressions and Objective Extubation Readiness Criteria in a Pediatric Intensive Care Unit.

作者信息

Marupudi Neelima K, Steurer-Muller Martina, Franzon Deborah

机构信息

Division of Pediatric Critical Care, Department of Pediatrics, University of Chicago, Chicago, Illinois, United States.

Pediatric Critical Care, University of California, San Francisco; San Francisco, California, United States.

出版信息

J Pediatr Intensive Care. 2022 Jan 21;13(3):253-260. doi: 10.1055/s-0041-1741403. eCollection 2024 Sep.

Abstract

Objective tools such as spontaneous breathing trials (SBT) aim to identify patients ready for extubation and shorten the length of mechanical ventilation (MV). Despite passing an SBT, patients sometimes are not extubated based on clinicians' subjective impressions. In this article, we explored the factors that influence the decision to extubate among pediatric intensivists and their association with objective criteria.  This is a single-center prospective observational study.  This study was conducted in an academic, multidisciplinary 20-bed pediatric intensive care unit (PICU).  The study group involves mechanically ventilated, orally intubated patients admitted to the PICU from January 1 to June 30, 2019.  Objective clinical data were collected for 650 MV days. Attending surveys about extubation readiness were completed for 419 (64.5%) MV days and 63 extubation events. Extubation occurred on 42% of days after passing an SBT. The primary reasons patients who passed an SBT were not extubated on days were unresolved lung pathology (66.6%) and fluid overload (37.6%). On days without extubation, there was no association between a specific reason for not extubating and SBT result ( > 0.05).  In this single-center study, the decision to extubate was not strongly associated with passing an SBT, indicating that clinician impressions, namely unresolved lung pathology and fluid overload, outweighed objective measures for determining extubation readiness. To mitigate morbidities and costs associated with unnecessarily prolonged intubations, a better-defined extubation readiness process is needed to guide the decision to extubate in the pediatric population.

摘要

诸如自主呼吸试验(SBT)等客观工具旨在识别准备好拔管的患者,并缩短机械通气(MV)的时长。尽管通过了SBT,但有时患者会基于临床医生的主观判断而未被拔管。在本文中,我们探讨了影响儿科重症监护医生拔管决策的因素及其与客观标准的关联。 这是一项单中心前瞻性观察性研究。 本研究在一家拥有20张床位的学术性多学科儿科重症监护病房(PICU)进行。 研究组包括2019年1月1日至6月30日入住PICU的机械通气、经口插管患者。 收集了650个机械通气日的客观临床数据。针对419个(64.5%)机械通气日和63次拔管事件完成了关于拔管准备情况的主治医师调查。通过SBT后,42%的日子里进行了拔管。通过SBT但未在当日拔管的患者的主要原因是肺部病变未解决(66.6%)和液体超负荷(37.6%)。在未拔管的日子里,未拔管的具体原因与SBT结果之间无关联(>0.05)。 在这项单中心研究中,拔管决策与通过SBT的关联不强,这表明临床医生的判断,即肺部病变未解决和液体超负荷,在确定拔管准备情况时比客观指标更具权重。为了减轻与不必要的长时间插管相关的发病率和成本,需要一个更明确的拔管准备流程来指导儿科患者的拔管决策。

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