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沙特阿拉伯新冠肺炎死亡病例的临床和流行病学特征:一项回顾性多中心研究。

Clinical and epidemiological characteristics of COVID-19 mortality in Saudi Arabia: A retrospective multi-center study.

作者信息

Mahmoud Mahmoud A, Altaluoni Alaa Anwar, Alshargi Abdulrahman Abdullah, Al-Zalabani Abdulmohsen H

机构信息

Department of Public Health, College of Medicine, Imam Muhammad Ibn Saud University, Riyadh, Saudi Arabia.

Senior Epidemiologist, Department of Medicine, Medical Vision College, Jeddah, Saudi Arabia.

出版信息

J Family Med Prim Care. 2024 Oct;13(10):4270-4275. doi: 10.4103/jfmpc.jfmpc_128_24. Epub 2024 Oct 18.

Abstract

BACKGROUND/AIM: Coronavirus disease 2019 (COVID-19) increased morbidity and mortality in health institutions worldwide. The present study describes the epidemiological and clinical characteristics of COVID-19 mortality rates. Investigating the factors that affect COVID-19 mortality will be helpful in reducing the burden of morbidity and mortality in healthcare systems.

MATERIALS AND METHODS

The current retrospective observational study was carried out in the Kingdom of Saudi Arabia. COVID-19 cases resulting in death were admitted to hospitals from March 2020 to June 2020. The epidemiological and clinical characteristics of these cases of COVID-19-related death were collected and evaluated.

RESULTS

A total of 3260 COVID-19 death cases were included. The mean age of the subjects was 55 years. COVID-19 deaths more frequently in patients aged 50-59 years, 60-69 years, and 40-49 years (26%, 22%, and 17%, respectively). A greater percentage of COVID-19-related deaths (47%) was observed in June than in March (>1%), April (15%), and May (37%). Men accounted for most death cases (76%) compared to women. The COVID-19 mortality rate was higher among non-Saudi (71%) than Saudis (29%). The highest COVID-19 mortality was observed in Tabuk Region, whereas the lowest was observed in Najran. The mean stay duration of COVID-19 cases in the intensive care unit (ICU) was 11 days. The independent -test indicated a statistically significant increase in the life expectancy (6 days) of ICU cases compared to non-ICU cases.

CONCLUSION

The findings suggest that older age, male gender, and non-Saudi are risk factors that enhance COVID-19 mortality rates, while medical care increases the life expectancy of COVID-19 cases.

摘要

背景/目的:2019冠状病毒病(COVID-19)在全球医疗机构中导致发病率和死亡率上升。本研究描述了COVID-19死亡率的流行病学和临床特征。调查影响COVID-19死亡率的因素将有助于减轻医疗系统中的发病和死亡负担。

材料与方法

当前的回顾性观察性研究在沙特阿拉伯王国进行。2020年3月至2020年6月期间,导致死亡的COVID-19病例被收治入院。收集并评估了这些COVID-19相关死亡病例的流行病学和临床特征。

结果

共纳入3260例COVID-19死亡病例。研究对象的平均年龄为55岁。COVID-19死亡在50-59岁、60-69岁和40-49岁的患者中更为常见(分别为26%、22%和17%)。6月观察到的COVID-19相关死亡百分比(47%)高于3月(>1%)、4月(15%)和5月(37%)。与女性相比,男性占大多数死亡病例(76%)。非沙特人(71%)的COVID-19死亡率高于沙特人(29%)。COVID-19死亡率最高的是塔布克地区,而最低的是奈季兰。COVID-19病例在重症监护病房(ICU)的平均停留时间为11天。独立t检验表明,与非ICU病例相比,ICU病例的预期寿命(6天)有统计学显著增加。

结论

研究结果表明,年龄较大、男性和非沙特人是增加COVID-19死亡率的危险因素,而医疗护理可提高COVID-19病例的预期寿命。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c02/11610894/98d0c1820f9a/JFMPC-13-4270-g001.jpg

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