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在聚氨酯工人中观察到的一种不寻常的角膜病及其在实验动物中的再现。

An unusual type of keratopathy observed in polyurethane workers and its reproduction in experimental animals.

作者信息

Potts A M, Rouse E F, Eiferman R A, Au P C

出版信息

Am J Ind Med. 1986;9(2):203-13. doi: 10.1002/ajim.4700090211.

DOI:10.1002/ajim.4700090211
PMID:3963001
Abstract

We have reported two cases of keratopathy in polyurethane workers that appear to be identical to those described by previous authors. We have been able to produce similar findings in the corneas of cats by exposing the eyes of anesthetized animals to the vapor of two of the amines used as catalysts in polyurethane manufacture. We were unable to reproduce these results with toluene diisocyanate. Therefore we support the previous suggestion that the amine catalysts are responsible for the distinctive keratopathy in polyurethane workers. We are unable to substantiate the claim that toluene diisocyanate is responsible for this phenomenon.

摘要

我们报告了两例聚氨酯工人角膜病病例,这些病例似乎与先前作者所描述的病例相同。通过将麻醉动物的眼睛暴露于聚氨酯制造中用作催化剂的两种胺的蒸汽中,我们在猫的角膜中产生了类似的发现。我们无法用甲苯二异氰酸酯重现这些结果。因此,我们支持先前的观点,即胺催化剂是聚氨酯工人独特角膜病的病因。我们无法证实甲苯二异氰酸酯是导致这种现象的说法。

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An unusual type of keratopathy observed in polyurethane workers and its reproduction in experimental animals.在聚氨酯工人中观察到的一种不寻常的角膜病及其在实验动物中的再现。
Am J Ind Med. 1986;9(2):203-13. doi: 10.1002/ajim.4700090211.
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