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心脏手术后房颤的影响:一项荟萃分析

Effect of Postoperative Atrial Fibrillation After Cardiac Surgery: A Meta-Analysis.

作者信息

Qu Fangzhou, Yang Wei, He Ni, Qu Shangcheng, Zhou Xiao, Ma Huayan, Jiang Xin

机构信息

Medical School, Xizang Minzu University, Xianyang, China.

Emergency Department, The Affiliated Hospital of Xizang University for Nationalities, Xianyang, China.

出版信息

Clin Cardiol. 2024 Dec;47(12):e70053. doi: 10.1002/clc.70053.

DOI:10.1002/clc.70053
PMID:39632617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11617639/
Abstract

BACKGROUND

A meta-analysis study was conducted to determine how to predict the effect of postoperative atrial fibrillation after cardiac surgery.

HYPOTHESIS

Long-term mortality and cardiovascular morbidity are linked to postoperative atrial fibrillation.

METHOD

Until August 2024, a comprehensive literature study was completed, and 3486 connected studies were revised. The 38 selected studies included 241 299 cardiac surgery participants at the beginning of the study. The odds ratio (OR) and 95% confidence intervals (CIs) were used to look at the effect of atrial fibrillation after heart surgery using two-sided methods and either a fixed or random model.

RESULTS

Individuals with cardiac surgery with postoperative atrial fibrillation had significantly higher mortality at 1 year (OR, 1.39; 95% CI, 1.12-1.72, p < 0.001), mortality at 5 years (OR, 1.61; 95% CI, 1.33-1.94, p < 0.001), mortality at 10 years (OR, 1.61; 95% CI, 1.39-1.87, p < 0.001), and overall stroke (OR, 1.61; 95% CI, 1.34-1.94, p < 0.001) compared to without postoperative atrial fibrillation.

CONCLUSIONS

Individuals with cardiac surgery with postoperative atrial fibrillation had significantly higher mortality at 1 year, mortality at 5 years, mortality at 10 years, and overall stroke compared to those without postoperative atrial fibrillation. To validate this discovery, more research and caution must be implemented when interacting with its values.

摘要

背景

进行了一项荟萃分析研究,以确定如何预测心脏手术后房颤的影响。

假设

长期死亡率和心血管疾病发病率与术后房颤有关。

方法

截至2024年8月,完成了一项全面的文献研究,共筛选了3486项相关研究。选定的38项研究在研究开始时纳入了241299名心脏手术参与者。采用双侧方法以及固定或随机模型,使用比值比(OR)和95%置信区间(CI)来观察心脏手术后房颤的影响。

结果

与无术后房颤的个体相比,有术后房颤的心脏手术个体在1年时死亡率显著更高(OR,1.39;95%CI,1.12 - 1.72,p < 0.001),5年时死亡率(OR,1.61;95%CI,1.33 - 1.94,p < 0.001),10年时死亡率(OR,1.61;95%CI,1.39 - 1.87,p < 0.001),以及总体卒中发生率(OR,1.61;95%CI,1.34 - 1.94,p < 0.001)。

结论

与无术后房颤的个体相比,有术后房颤的心脏手术个体在1年、5年、10年时死亡率显著更高,总体卒中发生率也更高。为验证这一发现,在涉及其数值时必须进行更多研究并谨慎对待。

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本文引用的文献

1
Postoperative atrial fibrillation is associated with long-term morbidity and mortality in older adults: Analysis from the SWEDEHEART Registry.术后房颤与老年人的长期发病率和死亡率相关:来自瑞典心脏注册研究的分析
JTCVS Open. 2024 Mar 12;19:116-130. doi: 10.1016/j.xjon.2024.03.001. eCollection 2024 Jun.
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Recurrence of Atrial Fibrillation in Patients With New-Onset Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting.冠状动脉旁路移植术后新发术后心房颤动患者心房颤动的复发。
JAMA Netw Open. 2024 Mar 4;7(3):e241537. doi: 10.1001/jamanetworkopen.2024.1537.
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Long-Term Effects of Postoperative Atrial Fibrillation following Mitral Valve Surgery.
二尖瓣手术后房颤的长期影响
J Cardiovasc Dev Dis. 2023 Jul 16;10(7):302. doi: 10.3390/jcdd10070302.
4
Associations between new-onset postoperative atrial fibrillation and long-term outcome in patients undergoing surgical aortic valve replacement.主动脉瓣置换术后新发心房颤动与手术患者长期预后的关系。
Eur J Cardiothorac Surg. 2023 May 2;63(5). doi: 10.1093/ejcts/ezad103.
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Long-Term Outcomes of Preoperative Atrial Fibrillation in Cardiac Surgery.心脏手术中术前房颤的长期预后
J Chest Surg. 2022 Oct 5;55(5):378-387. doi: 10.5090/jcs.21.146. Epub 2022 Jul 13.
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Effect of postoperative atrial fibrillation on early and mid-term outcomes of coronary artery bypass graft surgery.术后心房颤动对冠状动脉旁路移植术近期和中期结果的影响。
Eur J Cardiothorac Surg. 2022 Aug 3;62(3). doi: 10.1093/ejcts/ezac264.
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Effect of mutation and vaccination on spread, severity, and mortality of COVID-19 disease.新冠病毒疾病的传播、严重程度和死亡率的突变和疫苗接种影响。
J Med Virol. 2022 Jan;94(1):197-204. doi: 10.1002/jmv.27293. Epub 2021 Aug 30.
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Early pharmacologic conversion of atrial fibrillation after off-pump coronary artery bypass grafting.非体外循环冠状动脉搭桥术后房颤的早期药物复律
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New-Onset Perioperative Atrial Fibrillation After Coronary Artery Bypass Grafting and Long-Term Risk of Adverse Events: An Analysis From the CORONARY Trial.冠状动脉旁路移植术后新发围术期心房颤动与不良事件长期风险:CORONARY 试验分析。
J Am Heart Assoc. 2021 Jun 15;10(12):e020426. doi: 10.1161/JAHA.120.020426. Epub 2021 May 29.
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Repurposing of some anti-infective drugs for COVID-19 treatment: A surveillance study supported by an in silico investigation.抗传染药物再利用治疗 COVID-19:一项由计算机模拟研究支持的监测研究。
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