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心脏手术后房颤的影响:一项荟萃分析

Effect of Postoperative Atrial Fibrillation After Cardiac Surgery: A Meta-Analysis.

作者信息

Qu Fangzhou, Yang Wei, He Ni, Qu Shangcheng, Zhou Xiao, Ma Huayan, Jiang Xin

机构信息

Medical School, Xizang Minzu University, Xianyang, China.

Emergency Department, The Affiliated Hospital of Xizang University for Nationalities, Xianyang, China.

出版信息

Clin Cardiol. 2024 Dec;47(12):e70053. doi: 10.1002/clc.70053.

Abstract

BACKGROUND

A meta-analysis study was conducted to determine how to predict the effect of postoperative atrial fibrillation after cardiac surgery.

HYPOTHESIS

Long-term mortality and cardiovascular morbidity are linked to postoperative atrial fibrillation.

METHOD

Until August 2024, a comprehensive literature study was completed, and 3486 connected studies were revised. The 38 selected studies included 241 299 cardiac surgery participants at the beginning of the study. The odds ratio (OR) and 95% confidence intervals (CIs) were used to look at the effect of atrial fibrillation after heart surgery using two-sided methods and either a fixed or random model.

RESULTS

Individuals with cardiac surgery with postoperative atrial fibrillation had significantly higher mortality at 1 year (OR, 1.39; 95% CI, 1.12-1.72, p < 0.001), mortality at 5 years (OR, 1.61; 95% CI, 1.33-1.94, p < 0.001), mortality at 10 years (OR, 1.61; 95% CI, 1.39-1.87, p < 0.001), and overall stroke (OR, 1.61; 95% CI, 1.34-1.94, p < 0.001) compared to without postoperative atrial fibrillation.

CONCLUSIONS

Individuals with cardiac surgery with postoperative atrial fibrillation had significantly higher mortality at 1 year, mortality at 5 years, mortality at 10 years, and overall stroke compared to those without postoperative atrial fibrillation. To validate this discovery, more research and caution must be implemented when interacting with its values.

摘要

背景

进行了一项荟萃分析研究,以确定如何预测心脏手术后房颤的影响。

假设

长期死亡率和心血管疾病发病率与术后房颤有关。

方法

截至2024年8月,完成了一项全面的文献研究,共筛选了3486项相关研究。选定的38项研究在研究开始时纳入了241299名心脏手术参与者。采用双侧方法以及固定或随机模型,使用比值比(OR)和95%置信区间(CI)来观察心脏手术后房颤的影响。

结果

与无术后房颤的个体相比,有术后房颤的心脏手术个体在1年时死亡率显著更高(OR,1.39;95%CI,1.12 - 1.72,p < 0.001),5年时死亡率(OR,1.61;95%CI,1.33 - 1.94,p < 0.001),10年时死亡率(OR,1.61;95%CI,1.39 - 1.87,p < 0.001),以及总体卒中发生率(OR,1.61;95%CI,1.34 - 1.94,p < 0.001)。

结论

与无术后房颤的个体相比,有术后房颤的心脏手术个体在1年、5年、10年时死亡率显著更高,总体卒中发生率也更高。为验证这一发现,在涉及其数值时必须进行更多研究并谨慎对待。

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