Wang Lei, Li Guangjian, He Zhongliang
Department of Thoracic Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Peking University Cancer Hospital Yunnan, No.519, Kunzhou Rd, Kunming, 650106, Yunnan, China.
Department of Cardiothoracic Surgery, Tongde Hospital of Zhejiang Province, Hangzhou, 310012, Zhejiang, China.
J Cardiothorac Surg. 2024 Dec 4;19(1):641. doi: 10.1186/s13019-024-03171-2.
Chronic empyema is usually considered to be very challenging in clinical management and has a high mortality rate. On this basis, if combined with bronchopleural fistula (BPF) and huge irregular abscess cavity, there are not many treatment options available, and some patients may even develop cachexia due to long-term chronic consumption. The application of pedicled combined muscle flaps to repair and reconstruct according to the region of abscess cavity may improve the quality of life for such complex cases.
A 59-year-old male patient underwent surgical treatment for lung squamous cell carcinoma 2 years ago. Due to the low differentiation of malignant tumor, empyema complicated with BPF occurred after the fourth cycle of chemotherapy. His past medical history was free of other illnesses. The patient was admitted to our hospital for further treatment because of long-term chest tube drainage and obvious respiratory irritation symptoms such as cough during body position change. Chest computed tomography (CT) scan revealed a left-sided hydropneumothorax. Bronchoscopy revealed BPF. Considering that the volume of the abscess cavity did not shrink significantly after long-term drainage, we chose first-stage surgery to complete the debridement of empyema and the closure of the fistula. In the second-stage surgery, the combined pedicled muscle flaps were used to complete the filling in different areas of the huge irregular residual cavity. This surgical mode of staging and sub-regional treatment of abscess cavity has achieved satisfactory clinical results.
Utilizing the pedicled combined muscle flaps to address chronic empyema accompanied by a huge irregular abscess cavity shows promise as a treatment method for eliminating residual cavity in various regions.
慢性脓胸通常被认为在临床管理中极具挑战性,且死亡率很高。在此基础上,如果合并支气管胸膜瘘(BPF)和巨大不规则脓肿腔,则可用的治疗选择不多,一些患者甚至可能因长期慢性消耗而出现恶病质。根据脓肿腔的区域应用带蒂联合肌瓣进行修复和重建,可能会改善此类复杂病例的生活质量。
一名59岁男性患者于2年前接受了肺鳞状细胞癌的手术治疗。由于恶性肿瘤分化程度低,在化疗第四周期后发生了脓胸合并BPF。他既往无其他疾病史。因长期胸腔闭式引流及体位改变时咳嗽等明显的呼吸道刺激症状,患者入住我院进一步治疗。胸部计算机断层扫描(CT)显示左侧液气胸。支气管镜检查发现BPF。考虑到长期引流后脓肿腔体积无明显缩小,我们选择一期手术完成脓胸清创和瘘口闭合。在二期手术中,使用带蒂联合肌瓣对巨大不规则残留腔的不同区域进行填充。这种脓肿腔分期和分区治疗的手术方式取得了满意的临床效果。
利用带蒂联合肌瓣治疗伴有巨大不规则脓肿腔的慢性脓胸,作为一种消除各区域残留腔的治疗方法显示出前景。