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成人慢性肠衰竭与短肠综合征:最新进展

Chronic Intestinal Failure and Short Bowel Syndrome in Adults: The State of the Art.

作者信息

Vara-Luiz Francisco, Glória Luísa, Mendes Ivo, Carlos Sandra, Guerra Paula, Nunes Gonçalo, Oliveira Cátia Sofia, Ferreira Andreia, Santos Ana Paula, Fonseca Jorge

机构信息

GENE - Artificial Feeding Team, Gastroenterology Department, Hospital Garcia de Orta, Almada, Portugal.

Aging Lab, Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.

出版信息

GE Port J Gastroenterol. 2024 May 23;31(6):388-400. doi: 10.1159/000538938. eCollection 2024 Dec.

Abstract

BACKGROUND

Short bowel syndrome (SBS) is a devastating malabsorptive condition and the most common cause of chronic intestinal failure (CIF). During the intestinal rehabilitation process, patients may need parenteral support for months or years, parenteral nutrition (PN), or hydration/electrolyte supplementation, as a bridge for the desired enteral autonomy.

SUMMARY

Several classification criteria have been highlighted to reflect different perspectives in CIF. The management of CIF-SBS in adults is a multidisciplinary process that aims to reduce gastrointestinal secretions, slow transit, correct/prevent malnutrition, dehydration, and specific nutrient deficiencies, and prevent refeeding syndrome. The nutritional support team should have the expertise to take care of these complex patients: fluid support; oral, enteral, and PN; disease/PN-related complications; pharmacologic treatment; and surgical prevention/treatment.

KEY MESSAGES

CIF-SBS is a complex disease with undesired consequences, if not adequately identified and managed. A comprehensive approach performed by a multidisciplinary team is essential to reduce PN dependence, promote enteral independence, and improve quality of life.

摘要

背景

短肠综合征(SBS)是一种严重的吸收不良疾病,也是慢性肠衰竭(CIF)最常见的病因。在肠道康复过程中,患者可能需要数月或数年的肠外支持,即肠外营养(PN),或补充水分/电解质,作为实现理想肠内自主的桥梁。

总结

已强调了几种分类标准,以反映CIF的不同观点。成人CIF-SBS的管理是一个多学科过程,旨在减少胃肠道分泌、减缓转运、纠正/预防营养不良、脱水和特定营养素缺乏,并预防再喂养综合征。营养支持团队应具备照顾这些复杂患者的专业知识:液体支持;口服、肠内和PN;疾病/PN相关并发症;药物治疗;以及手术预防/治疗。

关键信息

如果未得到充分识别和管理,CIF-SBS是一种会产生不良后果的复杂疾病。多学科团队采取的综合方法对于减少PN依赖、促进肠内自主和提高生活质量至关重要。

相似文献

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Chronic Intestinal Failure and Short Bowel Syndrome in Adults: The State of the Art.成人慢性肠衰竭与短肠综合征:最新进展
GE Port J Gastroenterol. 2024 May 23;31(6):388-400. doi: 10.1159/000538938. eCollection 2024 Dec.

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