Suppr超能文献

短肠综合征的自体肠道重建手术:何种手术、何时进行以及为何进行

Autologous Intestinal Reconstruction Surgery in Short Bowel Syndrome: Which, When, and Why.

作者信息

Boroni Giovanni, Parolini Filippo, Stern Maria Vittoria, Moglia Cristina, Alberti Daniele

机构信息

Department of Paediatric Surgery, ASST Spedali Civili di Brescia, Brescia, Italy.

Department of Paediatric Surgery, University of Brescia, Brescia, Italy.

出版信息

Front Nutr. 2022 Apr 7;9:861093. doi: 10.3389/fnut.2022.861093. eCollection 2022.

Abstract

Short bowel syndrome (SBS), secondary to any natural loss or after any extensive bowel resection for congenital malformations or acquired disease, is the most common cause of intestinal failure in children. Extensive introduction of parenteral nutrition (PN) has dramatically changed the outcome of these patients, allowing for long-term survival. The main goal in children with SBS remains to be increasing enteral tolerance and weaning from PN support. Post resection intestinal adaptation allows for achievement of enteral autonomy in a subset of these patients, but the inability to progress in enteral tolerance exposes others to long-term complications of PN. Autologous intestinal reconstruction surgery (AIRS) can facilitate the fulfilment of enteral autonomy, maximizing the absorptive potential of the remaining gut. All the different intestinal reconstruction techniques, from simple procedures like tapering, reversed segments, and colon interposition, to more complex lengthening procedures (LILT: longitudinal intestinal lengthening and tailoring, STEP: serial transverse enteroplasty, and SILT: spiral intestinal lengthening and tailoring) and techniques designed for peculiar problems like controlled intestinal tissue expansion or duodenal lengthening are presented. AIRS indications, clinical applications, and results reported in the literature are reviewed.

摘要

短肠综合征(SBS)继发于任何自然性肠丢失或因先天性畸形或后天性疾病进行广泛肠切除术后,是儿童肠衰竭最常见的原因。肠外营养(PN)的广泛应用显著改变了这些患者的预后,使其能够长期存活。SBS患儿的主要目标仍然是提高肠道耐受性并逐渐停用PN支持。切除术后的肠道适应性可使部分此类患者实现肠道自主,但肠道耐受性无法改善则会使其他患者面临PN的长期并发症。自体肠道重建手术(AIRS)有助于实现肠道自主,最大限度地发挥剩余肠道的吸收潜力。本文介绍了所有不同的肠道重建技术,从诸如肠管缩窄、肠段翻转和结肠间置等简单手术,到更为复杂的延长手术(LILT:纵向肠道延长和裁剪术、STEP:系列横断肠成形术、SILT:螺旋式肠道延长和裁剪术)以及针对特殊问题设计的技术,如可控性肠道组织扩张或十二指肠延长术。对AIRS的适应证、临床应用及文献报道的结果进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac74/9023091/34cfe573411e/fnut-09-861093-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验