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无系统性白血病的皮肤髓系白血病:一例报告

Myeloid leukemia cutis in the absence of systemic leukemia: A case report.

作者信息

Taha Mohamad R, Tyring Stephen K

机构信息

School of Medicine, Texas A&M University Health Science Center, Bryan, TX, USA.

Center for Clinical Studies, Webster, TX, USA.

出版信息

SAGE Open Med Case Rep. 2024 Dec 4;12:2050313X241304880. doi: 10.1177/2050313X241304880. eCollection 2024.

DOI:10.1177/2050313X241304880
PMID:39634071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11615972/
Abstract

Leukemia cutis (LC) is an uncommon cutaneous manifestation of leukemia that involves the leukocytic infiltration of the skin. LC typically presents after a diagnosis of leukemia has been made but may rarely appear before confirmation of the disease. In this report, we describe the case of an 86-year-old male presenting with LC prior to a clear diagnosis of leukemia in the blood. This case highlights the importance of early recognition of LC lesions, to ensure earlier detection of the neoplasm, particularly when they present as the first sign of disease.

摘要

皮肤白血病(LC)是白血病一种不常见的皮肤表现,涉及皮肤的白细胞浸润。LC通常在白血病确诊后出现,但很少在疾病确诊前出现。在本报告中,我们描述了一例86岁男性在血液中白血病明确诊断之前出现LC的病例。该病例强调了早期识别LC病变的重要性,以确保更早地发现肿瘤,尤其是当它们作为疾病的首发症状出现时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52af/11615972/21f556467ece/10.1177_2050313X241304880-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52af/11615972/c942f1a2b13a/10.1177_2050313X241304880-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52af/11615972/fee9309c9d9f/10.1177_2050313X241304880-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52af/11615972/21f556467ece/10.1177_2050313X241304880-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52af/11615972/c942f1a2b13a/10.1177_2050313X241304880-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52af/11615972/fee9309c9d9f/10.1177_2050313X241304880-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52af/11615972/21f556467ece/10.1177_2050313X241304880-fig3.jpg

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本文引用的文献

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Acute myeloid leukemia cutis with KMT2A::MLLT3 fusion presenting with leonine facies.
Leuk Res Rep. 2023 Nov 24;21:100400. doi: 10.1016/j.lrr.2023.100400. eCollection 2024.
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Leukemia Cutis-The Current View on Pathogenesis, Diagnosis, and Treatment.皮肤白血病——关于发病机制、诊断和治疗的当前观点
Cancers (Basel). 2023 Nov 13;15(22):5393. doi: 10.3390/cancers15225393.
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A case of aleukemic leukemia cutis after COVID-19 infection presenting as facial rash.COVID-19 感染后继发无白细胞性白血病皮肤表现为面部皮疹 1 例
J Cutan Pathol. 2023 Jul;50(7):606-610. doi: 10.1111/cup.14431. Epub 2023 Apr 17.
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Vulvar leukemia cutis: A case report and review of the literature.外阴皮肤白血病:一例报告并文献复习
JAAD Case Rep. 2022 Nov 17;31:97-101. doi: 10.1016/j.jdcr.2022.10.039. eCollection 2023 Jan.
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