Syed Kunzah A, Lafaro Kelly J, Afghani Elham
Division of Gastroenterology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Department of Medicine, Pancreatitis Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Turk J Gastroenterol. 2024 Nov 4;36(1):6-14. doi: 10.5152/tjg.2024.24124.
Pancreatic cystic lesions (PCLs) are frequent incidental findings with an increasing prevalence with age. For these significant lesions, accurate characterization of cyst type and prediction of the risk of malignant progression are crucial for specific management, such as deciding to monitor a lesion or pursue surgical intervention. Fortunately, endoscopy-based diagnostic and therapeutic techniques like endoscopic ultrasound with fine needle aspiration, confocal endomicroscopy, through-the-needle biopsy, contrast-enhanced endoscopic ultrasound, ablation, and pancreatoscopy have enabled increasingly accurate diagnoses of PCLs. Surgical management should be considered in certain cases. This narrative review's objective is to appraise and synthesize the salient literature on the endoscopic and surgical management of PCLs to aid clinician decision-making. We analyze the current data and explore the benefits, challenges, and future prospects of endoscopy and surgery for pancreatic cysts.
胰腺囊性病变（PCLs）是常见的偶然发现，其患病率随年龄增长而增加。对于这些重要病变，准确区分囊肿类型并预测恶性进展风险对于具体管理至关重要，例如决定对病变进行监测还是采取手术干预。幸运的是，基于内镜的诊断和治疗技术，如内镜超声引导下细针穿刺、共聚焦内镜显微术、经针活检、对比增强内镜超声、消融和胰管镜检查，已使PCLs的诊断越来越准确。在某些情况下应考虑手术治疗。本叙述性综述的目的是评估和综合关于PCLs内镜和手术治疗的重要文献，以帮助临床医生做出决策。我们分析当前数据，探讨内镜和手术治疗胰腺囊肿的益处、挑战及未来前景。
