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重度哮喘患者接受第二次支气管热成形术的病例系列

A Case Series of Patients Undergoing Bronchial Thermoplasty a Second Time for Severe Asthma.

作者信息

Foo Chuan T, Langton David, Thien Francis

机构信息

Department of Respiratory Medicine, Eastern Health, Melbourne, VIC, Australia.

Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia.

出版信息

J Asthma Allergy. 2024 Nov 30;17:1239-1245. doi: 10.2147/JAA.S492730. eCollection 2024.

Abstract

Bronchial thermoplasty is a treatment option for patients with severe asthma. We report a case series of 6 patients who underwent bronchial thermoplasty on two separate occasions for poorly controlled asthma. The repeat procedures were well tolerated with no unexpected complications. One patient developed a focal area of mild bronchiectasis on imaging 6-months after repeat treatment, but this was not felt to be clinically relevant. Individual responses to repeat bronchial thermoplasty were varied, with some patients showing great improvement after treatment, whereas others did not. This series highlights the safety and feasibility of performing repeat ablation on previously ablated airways, as well as the potential clinical benefit in a select group of patients.

摘要

支气管热成形术是重度哮喘患者的一种治疗选择。我们报告了一组6例患者的病例系列,这些患者因哮喘控制不佳在两个不同时间接受了支气管热成形术。重复手术耐受性良好,未出现意外并发症。1例患者在重复治疗6个月后的影像学检查中出现了一个轻度支气管扩张的局灶性区域,但认为这在临床上不相关。个体对重复支气管热成形术的反应各不相同,一些患者治疗后有很大改善,而另一些患者则没有。该病例系列突出了对先前消融的气道进行重复消融的安全性和可行性,以及在特定患者群体中的潜在临床益处。

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