Brys Marieke, Den Hondt Stien, Saey Veronique, Claerebout Edwin, Chiers Koen
Laboratory of Veterinary Pathology, Department of Pathobiology, Pharmacology and Zoological Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
DAP Stien Den Hondt, Lier, Belgium.
Front Vet Sci. 2024 Nov 20;11:1427400. doi: 10.3389/fvets.2024.1427400. eCollection 2024.
Various draft horse breeds, especially breeds with abundant feathering on the lower limbs, are known to be susceptible to chorioptic mange. Clinical signs of chorioptic mange encompass intense pruritus leading to self-mutilation and hair loss, thickening of the epidermis, and the formation of hyperkeratotic crusts and scabs. Despite the frequent occurrence and high impact of this condition, treatment options are limited, with a conspicuous absence of registered products formulated for equines, and especially foals. This limited availability of approved products highlights the necessity for alternative approaches to effectively address chorioptic mange in draft horse populations, given the severity of the clinical signs and their negative impact on the well-being of infested horses.
Two 9-months old Belgian draft horse foals with clinical signs of severe pruritus and skin scaling on the distal legs were included. Both horses tested positive for living mites by means of superficial skin scrapings. Topical treatment with ivermectin at a dose of 1 mg/kg body weight was applied twice with 1 week interval, directly onto the distal legs of the horses.
In both cases, the mites were morphologically identified as . Negative scrapings were obtained 7 days after the second treatment. Pruritus resolved in both horses within 2 days after the first treatment. Clinical signs consisting of skin scaling and crusting in the pastern region had resolved as well at 1 week and 3 weeks after the second treatment, respectively.
This case report presents the first successful treatment of two clinical cases of chorioptic mange in Belgian draft horse foals with 1 mg/kg topical ivermectin, applied directly onto the distal legs.
各种挽马品种，尤其是下肢有丰富羽状毛的品种，已知易患足螨病。足螨病的临床症状包括强烈瘙痒导致自残和脱毛、表皮增厚以及形成角化过度的痂皮和结痂。尽管这种疾病频繁发生且影响严重，但治疗选择有限，明显缺乏为马匹尤其是幼驹配制的注册产品。鉴于临床症状的严重性及其对患病马匹健康的负面影响，批准产品的有限可用性凸显了采用替代方法有效解决挽马群体中足螨病的必要性。
纳入了两匹9个月大的比利时挽马驹，它们的远端腿部有严重瘙痒和皮肤脱屑的临床症状。通过浅表皮肤刮片检查，两匹马的活螨检测均呈阳性。以1毫克/千克体重的剂量将伊维菌素直接涂抹在马的远端腿部，间隔1周进行两次局部治疗。
在这两个病例中，螨在形态学上被鉴定为 。第二次治疗7天后刮片结果为阴性。两匹马在第一次治疗后2天内瘙痒症状均得到缓解。分别在第二次治疗后1周和3周，跗关节区域的皮肤脱屑和结痂等临床症状也已消失。
本病例报告展示了首次成功治疗两例比利时挽马驹足螨病临床病例的情况，采用1毫克/千克的伊维菌素直接局部涂抹在远端腿部。
