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新冠病毒感染与急性髓系白血病:可能的关联?

COVID-19 Infection and Acute Myeloid Leukemia: A Likely Marriage?

作者信息

Al-Midfai Younus, Bengio Moshe, Aneja Pallavi

机构信息

Internal Medicine, HCA Healthcare Westside Hospital, Plantation, USA.

Internal Medicine, Northwest Medical Center, Margate, USA.

出版信息

Cureus. 2024 Nov 3;16(11):e72940. doi: 10.7759/cureus.72940. eCollection 2024 Nov.

DOI:10.7759/cureus.72940
PMID:39634968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11614716/
Abstract

In the early era of COVID-19, characterization of long-term complications was unfeasible. But in early 2021, the authors came across a patient with a new diagnosis of Acute Myeloid Leukemia (AML) that was highly suspected as being secondary to a previous COVID-19 infection. The similarities of this anomaly to Hodgkin Lymphoma occurring after Epstein Barr Virus prompted the authors to perform a qualitative review of the literature for a possible pathway of how COVID-19 can cause AML.

摘要

在新冠疫情早期,对长期并发症进行特征描述是不可行的。但在2021年初,作者遇到一名新诊断为急性髓系白血病(AML)的患者,高度怀疑该病继发于先前的新冠病毒感染。这种异常情况与爱泼斯坦-巴尔病毒感染后发生的霍奇金淋巴瘤的相似性,促使作者对文献进行定性综述,以探寻新冠病毒导致急性髓系白血病的可能途径。

相似文献

1
COVID-19 Infection and Acute Myeloid Leukemia: A Likely Marriage?新冠病毒感染与急性髓系白血病:可能的关联?
Cureus. 2024 Nov 3;16(11):e72940. doi: 10.7759/cureus.72940. eCollection 2024 Nov.
2
Epstein-Barr virus-positive diffuse large B-cell lymphoma following acute myeloid leukemia: a common clonal origin indicated by chromosomal translocation t(3;4)(p25;q21).急性髓系白血病后发生的爱泼斯坦-巴尔病毒阳性弥漫性大B细胞淋巴瘤:染色体易位t(3;4)(p25;q21)提示共同的克隆起源
Int J Hematol. 2015 Oct;102(4):482-7. doi: 10.1007/s12185-015-1802-4. Epub 2015 May 8.
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Concurrent classical Hodgkin lymphoma and plasmablastic lymphoma in a patient with chronic lymphocytic leukemia/small lymphocytic lymphoma treated with fludarabine: a dimorphic presentation of iatrogenic immunodeficiency-associated lymphoproliferative disorder with evidence suggestive of multiclonal transformability of B cells by Epstein-Barr virus.慢性淋巴细胞白血病/小淋巴细胞淋巴瘤患者接受氟达拉滨治疗后并发经典霍奇金淋巴瘤和浆母细胞淋巴瘤:医源性免疫缺陷相关淋巴增生性疾病的二相表现,具有 EBV 导致 B 细胞多克隆转化的证据
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Clin Res Hepatol Gastroenterol. 2022 Oct;46(8):102000. doi: 10.1016/j.clinre.2022.102000. Epub 2022 Aug 3.

本文引用的文献

1
Long COVID: major findings, mechanisms and recommendations.长新冠:主要发现、机制和建议。
Nat Rev Microbiol. 2023 Mar;21(3):133-146. doi: 10.1038/s41579-022-00846-2. Epub 2023 Jan 13.
2
More than 50 long-term effects of COVID-19: a systematic review and meta-analysis.COVID-19 的 50 多种长期影响:系统评价和荟萃分析。
Sci Rep. 2021 Aug 9;11(1):16144. doi: 10.1038/s41598-021-95565-8.
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Anti-inflammatory potential of Quercetin in COVID-19 treatment.槲皮素在COVID-19治疗中的抗炎潜力。
J Inflamm (Lond). 2021 Jan 28;18(1):3. doi: 10.1186/s12950-021-00268-6.
4
SARS-CoV-2 infection and overactivation of Nlrp3 inflammasome as a trigger of cytokine "storm" and risk factor for damage of hematopoietic stem cells.严重急性呼吸综合征冠状病毒 2 感染和 Nlrp3 炎性小体过度激活作为细胞因子“风暴”的触发因素和造血干细胞损伤的危险因素。
Leukemia. 2020 Jul;34(7):1726-1729. doi: 10.1038/s41375-020-0887-9. Epub 2020 Jun 1.
5
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)进入细胞依赖于 ACE2 和 TMPRSS2,可被一种临床验证的蛋白酶抑制剂所阻断。
Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5.
6
Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes.慢性免疫刺激可能是急性髓系白血病或骨髓增生异常综合征发展的一个诱因。
J Clin Oncol. 2011 Jul 20;29(21):2897-903. doi: 10.1200/JCO.2011.34.8540. Epub 2011 Jun 20.
7
A role for the renin-angiotensin system in hematopoiesis.肾素-血管紧张素系统在造血过程中的作用。
Haematologica. 2009 Jun;94(6):745-7. doi: 10.3324/haematol.2009.006965.
8
Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells.血管紧张素转换酶(CD143)的表达可识别并调节源自人类多能干细胞的原始成血管细胞。
Blood. 2008 Nov 1;112(9):3601-14. doi: 10.1182/blood-2008-03-144766. Epub 2008 Aug 26.
9
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N Engl J Med. 2003 Oct 2;349(14):1324-32. doi: 10.1056/NEJMoa023141.
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Childhood social environment and Hodgkin's disease.儿童期社会环境与霍奇金淋巴瘤
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