Guo Xin, Shen Li, Dou Jing, Lv Yaogai, Zhang Anning, Shi Fanchao, Xue Zhiqiang, Yu Yaqin, Jin Lina, Yao Yan
Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
Int J Environ Res Public Health. 2017 Nov 10;14(11):1368. doi: 10.3390/ijerph14111368.
: Diabetes mellitus (DM) has become a major public health problem in China. Although a number of researchers have investigated DM risk factors, little is known about the associations between values of fasting blood glucose (FBG) and influencing factors. This study aims to explore these associations by the quantile regression (QR) model. : A cross-sectional survey based on a sample of 23,050 adults aged 18 to 79 years was conducted in Jilin in 2012, and some subjects were excluded due to missing values with respect to necessary variables or having glycemic control, in accordance with the purposes of this study. Finally, in total 14,698 people were included in this study. QR was performed to identify the factors influencing the level of FBG in different quantiles of FBG. The distribution of FBG status was different between males and females (² = 175.30, < 0.001). The QR model provided more detailed views on the associations of FBG with different factors and revealed apparent quantile-related patterns separately for different factors. Body mass index (BMI) was positively associated with the low and middle quantiles of FBG. Waist circumference (WC) had a positive association with the high quantiles of FBG. : FBG had a positive association with BMI in normal FBG, and a positive association with WC in high FBG. Diet and alcohol intake were associated with FBG in normal FBG. FBG was more likely to be elevated in the elderly, female workers, and people with family history of DM.
糖尿病(DM)已成为中国一个主要的公共卫生问题。尽管许多研究人员已对糖尿病风险因素进行了调查,但对于空腹血糖(FBG)值与影响因素之间的关联却知之甚少。本研究旨在通过分位数回归(QR)模型探索这些关联。:2012年在吉林对23050名年龄在18至79岁的成年人进行了横断面调查,根据本研究目的,一些受试者因必要变量缺失值或血糖控制情况而被排除。最终,本研究共纳入14698人。采用分位数回归来确定在空腹血糖不同分位数下影响空腹血糖水平的因素。空腹血糖状态的分布在男性和女性之间存在差异(χ² = 175.30,P < 0.001)。分位数回归模型对空腹血糖与不同因素之间的关联提供了更详细的见解,并分别揭示了不同因素明显的分位数相关模式。体重指数(BMI)与空腹血糖的低、中分位数呈正相关。腰围(WC)与空腹血糖的高分位数呈正相关。:在正常空腹血糖水平下,空腹血糖与BMI呈正相关,在高空腹血糖水平下,空腹血糖与腰围呈正相关。饮食和酒精摄入与正常空腹血糖水平下的空腹血糖有关。老年人、女性工作者以及有糖尿病家族史的人群空腹血糖升高的可能性更大。