Zhang Qing-Biao, Liu Dan, Feng Jun-Bang, Du Chun-Qi, Li Chuan-Ming
Department of Medical Imaging, Chongqing Emergency Medical Center, Chongqing University Central Hospital, School of Medicine, Chongqing University, Chongqing 400014, China.
Department of Cardiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400000, China.
World J Radiol. 2024 Nov 28;16(11):703-707. doi: 10.4329/wjr.v16.i11.703.
Autoimmune pancreatitis (AIP) is a special type of chronic pancreatitis with clinical symptoms of obstructive jaundice and abdominal discomfort; this condition is caused by autoimmunity and marked by pancreatic fibrosis and dysfunction. Previous studies have revealed a close relationship between early pancreatic atrophy and the incidence rate of diabetes in type 1 AIP patients receiving steroid treatment. Shimada performed a long-term follow-up study and reported that the pancreatic volume (PV) of these patients initially exponentially decreased but then slowly decreased, which was considered to be an important factor related to diabetes; moreover, serum IgG4 levels were positively correlated with PV during follow-up. In this letter, regarding the original study presented by Shimada , we present our insights and discuss how multimodal medical imaging and artificial intelligence can be used to better assess the relationship between pancreatic morphological changes and diabetes in patients with AIP.
自身免疫性胰腺炎（AIP）是一种特殊类型的慢性胰腺炎，具有梗阻性黄疸和腹部不适的临床症状；这种疾病由自身免疫引起，以胰腺纤维化和功能障碍为特征。先前的研究表明，早期胰腺萎缩与接受类固醇治疗的1型AIP患者的糖尿病发病率之间存在密切关系。岛田进行了一项长期随访研究，并报告称这些患者的胰腺体积（PV）最初呈指数下降，但随后缓慢下降，这被认为是与糖尿病相关的一个重要因素；此外，随访期间血清IgG4水平与PV呈正相关。在这封信中，关于岛田提出的原始研究，我们提出我们的见解，并讨论如何使用多模态医学成像和人工智能来更好地评估AIP患者胰腺形态变化与糖尿病之间的关系。
