Saini Ravinder S, Vyas Rajesh, Mosaddad Seyed Ali, Heboyan Artak
Department of Dental Technology, COAMS, King Khalid University, Abha, Saudi Arabia.
Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
J Surg Oncol. 2025 Jun;131(7):1272-1283. doi: 10.1002/jso.28034. Epub 2024 Dec 5.
Oral cancer commonly affects various parts of the oral cavity, including the lips, tongue, gums, palate, and inner cheeks. Oral rehabilitation involves multiple approaches aimed at restoring and improving oral function, esthetics, and overall well-being. This study assessed the functional outcomes and quality of life in patients who underwent rehabilitation following an oral cancer diagnosis. A comprehensive literature search was performed across PubMed, Cochrane Library, Dimensions, ScienceDirect, CINAHL, and Google Scholar databases. The study included patients diagnosed with oral cancer who had undergone oral rehabilitation. Functional outcomes and quality of life were key selection criteria. The methodological quality of the included studies was assessed, and data were systematically extracted and analyzed. A significant relationship was observed between the type of maxillectomy and quality of life, with obturator retention and stability being critical factors. Radiotherapy was found to adversely impact oral function and implant survival rates, with a strong correlation between radiation treatment and reduced implant survival (p < 0.00001). Additionally, dentition and the timing of implant placement were associated with recurrence rates and adverse effects. The findings highlight the crucial role of oral rehabilitation in improving both functional outcomes and quality of life in oral cancer patients. This study underscores the importance of incorporating oral rehabilitation into oral cancer treatment to enhance patient recovery and overall health.
口腔癌通常会影响口腔的各个部位，包括嘴唇、舌头、牙龈、上颚和脸颊内侧。口腔修复涉及多种方法，旨在恢复和改善口腔功能、美观以及整体健康状况。本研究评估了口腔癌诊断后接受修复治疗的患者的功能结局和生活质量。在PubMed、Cochrane图书馆、Dimensions、ScienceDirect、CINAHL和谷歌学术数据库中进行了全面的文献检索。该研究纳入了诊断为口腔癌且接受过口腔修复的患者。功能结局和生活质量是关键的入选标准。评估了纳入研究的方法学质量，并系统地提取和分析了数据。观察到上颌骨切除术的类型与生活质量之间存在显著关系，其中赝复体的保留和稳定性是关键因素。发现放射治疗会对口腔功能和种植体存活率产生不利影响，放射治疗与种植体存活率降低之间存在很强的相关性（p < 0.00001）。此外，牙列和种植体植入时机与复发率和不良反应有关。研究结果突出了口腔修复在改善口腔癌患者功能结局和生活质量方面的关键作用。本研究强调了将口腔修复纳入口腔癌治疗以促进患者康复和整体健康的重要性。
