Bergin C, Müller N, Nichols D M, Lillington G, Hogg J C, Mullen B, Grymaloski M R, Osborne S, Paré P D
Am Rev Respir Dis. 1986 Apr;133(4):541-6. doi: 10.1164/arrd.1986.133.4.541.
To assess the accuracy of computed tomography (CT) in the diagnosis of emphysema, we performed CT on 32 patients prior to surgery for removal of suspected tumors. The CT scans were assessed visually for emphysema by 2 independent radiologists and 1 chest physician. Intraobserver and interobserver variation were assessed. Pathologic emphysema was graded on the resected lung specimens. These grades were correlated with the CT scores and with pulmonary function tests obtained prior to surgery. Significant correlation was found between the pathologic grade on resected lung specimens and the preoperative CT score of both the resected lobe (r greater than or equal to 0.57, p less than 0.001) and the whole lung (r greater than or equal to 0.63, p less than 0.001). Compared with pulmonary function tests, CT was a better predictor of emphysema and distinguished patients with moderate emphysema from patients with normal lungs. We conclude that CT is a useful adjunct in assessing the presence and severity of emphysema.
为评估计算机断层扫描（CT）诊断肺气肿的准确性，我们对32例因疑似肿瘤行手术切除的患者在术前进行了CT检查。由2名独立的放射科医生和1名胸科医生对CT扫描结果进行肺气肿的视觉评估。评估了观察者内和观察者间的差异。对切除的肺标本进行病理性肺气肿分级。这些分级与CT评分以及术前获得的肺功能测试结果相关。在切除的肺标本的病理分级与切除肺叶（r≥0.57，p<0.001）和全肺（r≥0.63，p<0.001）的术前CT评分之间发现了显著相关性。与肺功能测试相比，CT是肺气肿更好的预测指标，并且能够区分中度肺气肿患者和肺功能正常的患者。我们得出结论，CT在评估肺气肿的存在和严重程度方面是一种有用的辅助手段。
