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尽管兔体内存在抗半乳糖脑苷脂循环抗体,但再生的周围神经芽仍能正常髓鞘化。

Normal myelination of regenerating peripheral nerve sprouts despite circulating antibodies to galactocerebroside in rabbits.

作者信息

Stoll G, Reiners K, Schwendemann G, Heininger K, Toyka K V

出版信息

Ann Neurol. 1986 Feb;19(2):189-92. doi: 10.1002/ana.410190213.

Abstract

Rabbits were immunized with galactocerebroside and a crush lesion was created in the tibial nerve before the onset of experimental allergic neuritis. Normal regeneration and myelination of distal peripheral nerve sprouts occurred and was identical to that of controls, although circulating antigalactocerebroside antibodies were present and nerve roots showed typical signs of beginning experimental allergic neuritis.

摘要

用半乳糖脑苷脂对兔子进行免疫,在实验性变应性神经炎发作前,在胫神经上造成挤压损伤。尽管存在循环抗半乳糖脑苷脂抗体,且神经根显示出开始发生实验性变应性神经炎的典型迹象,但远端周围神经芽正常再生和髓鞘形成,且与对照组相同。

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