Chang Youngs, Hwang Soo-Hee, Bai Haibin, Park Seowoo, Cho Eunbyul, Kim Dohoung, Lee Hyejin, Lee Jin Yong
Department of Preventive Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
HIRA Policy Research Institute, Health Insurance Review & Assessment Service (HIRA), Wonju, Korea.
J Prev Med Public Health. 2025 Jan;58(1):60-71. doi: 10.3961/jpmph.24.432. Epub 2024 Oct 28.
This study aimed to investigate the impact of coronavirus disease 2019 (COVID-19) on admission rates and in-hospital mortality among patients with ischemic and hemorrhagic stroke.
We constructed a dataset detailing the monthly hospitalizations and mortality rates of inpatients with stroke from January 2017 to December 2021. Employing an interrupted time series analysis, we explored the impact of COVID-19 on hospitalizations and 30-day in-hospital mortality among stroke patients.
The number of ischemic stroke admissions decreased by 18.5%, from 5335 to 4348, immediately following the COVID-19 outbreak (p<0.001). The in-hospital mortality rate for ischemic stroke increased slightly from 3.3% to 3.4% immediately after the outbreak, although it showed a decreasing trend over time. The number of hemorrhagic stroke admissions fell by 7.5%, from 2014 to 1864, immediately following the COVID-19 outbreak. The 30-day in-hospital mortality rate for hemorrhagic stroke initially decreased from 12.9% to 12.7%, but subsequently showed an increasing trend.
We confirmed that COVID-19 impacted both the admission and death rates of stroke patients. The admission rate for both ischemic and hemorrhagic strokes decreased, while in-hospital mortality increased. Specifically, in-hospital mortality from ischemic stroke rose initially after the outbreak before stabilizing. Additionally, our findings indicate variable effects based on sex, age, and socioeconomic status, suggesting that certain groups may be more susceptible. This underscores the need to identify and support vulnerable populations to mitigate adverse health outcomes.
本研究旨在调查2019冠状病毒病（COVID-19）对缺血性和出血性中风患者入院率及住院死亡率的影响。
我们构建了一个数据集，详细记录了2017年1月至2021年12月中风住院患者的月度住院情况和死亡率。采用中断时间序列分析，我们探讨了COVID-19对中风患者住院情况和30天住院死亡率的影响。
COVID-19疫情爆发后，缺血性中风入院人数立即下降了18.5%，从5335人降至4348人（p<0.001）。缺血性中风的住院死亡率在疫情爆发后立即略有上升，从3.3%升至3.4%，不过随着时间推移呈下降趋势。出血性中风入院人数在COVID-19疫情爆发后立即下降了7.5%，从2014人降至1864人。出血性中风的30天住院死亡率最初从12.9%降至12.7%，但随后呈上升趋势。
我们证实COVID-19对中风患者的入院率和死亡率均有影响。缺血性和出血性中风的入院率均下降，而住院死亡率上升。具体而言，缺血性中风的住院死亡率在疫情爆发后最初上升，之后趋于稳定。此外，我们的研究结果表明，基于性别、年龄和社会经济地位存在不同影响，这表明某些群体可能更易受影响。这凸显了识别和支持弱势群体以减轻不良健康结局的必要性。
