Pham Anh, Smith Julia, Card Kiffer G, Byers Kaylee A, Khor Esther
Faculty of Health Sciences, Simon Fraser University, Blusson Hall, Room 11300, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.
Pacific Institute on Pathogens, Pandemics and Society, Simon Fraser University, Burnaby, Canada.
Sci Rep. 2024 Dec 6;14(1):30410. doi: 10.1038/s41598-024-81275-4.
This study explores the health-related quality of life (HRQoL) experienced by patients with Long COVD-19 using data from British Columbia's post-COVID-19 Recovery Clinics. A retrospective cohort of 3463 patients was analyzed to assess HRQoL through the EQ-5D-5L questionnaire which includes five dimensions (mobility, self-care, usual activities, physical health, and mental health) administered to patients; responses were analyzed using the Visual Analogue Score (VAS). Notably, 95% of participants reported HRQoL scores below 90, with 50% scoring under 60, indicating significant impacts on their well-being. The analysis revealed that HRQoL is significantly influenced by various social determinants of health (SDoH), including age, sex, employment status, and ethnicity, each showing distinct correlations with HRQoL dimensions and overall VAS scores. Specifically, older age was associated with decreased mobility and increased pain/discomfort but less anxiety and depression, highlighting varying impacts across the age spectrum. The study highlights the multifaceted impacts of Long COVID on the lives of patients and underscores the necessity of targeted strategies to improve HRQoL among diverse groups, considering specific SDoH. Such a comprehensive approach could lead to more equitable health outcomes and support the development of tailored public health policies aimed at the recovery and rehabilitation of Long COVID sufferers.
本研究利用不列颠哥伦比亚省新冠后康复诊所的数据，探讨了长新冠患者所经历的健康相关生活质量（HRQoL）。对3463名患者的回顾性队列进行了分析，通过EQ-5D-5L问卷评估健康相关生活质量，该问卷包括五个维度（行动能力、自我护理、日常活动、身体健康和心理健康），并对患者进行了问卷调查；使用视觉模拟评分法（VAS）对回答进行分析。值得注意的是，95%的参与者报告健康相关生活质量得分低于90，其中50%的得分低于60，这表明对他们的幸福感有显著影响。分析表明，健康相关生活质量受到各种健康社会决定因素（SDoH）的显著影响，包括年龄、性别、就业状况和种族，每种因素与健康相关生活质量维度和总体VAS得分都显示出不同的相关性。具体而言，年龄较大与行动能力下降、疼痛/不适增加相关，但焦虑和抑郁较少，这突出了不同年龄段的不同影响。该研究强调了长新冠对患者生活的多方面影响，并强调了考虑特定健康社会决定因素的针对性策略对于改善不同群体健康相关生活质量的必要性。这样一种全面的方法可能会带来更公平的健康结果，并支持制定旨在帮助长新冠患者康复和恢复的定制公共卫生政策。
