Huang Guanjie, Ma Jianzhong, Chen Jie, Zhang Wenbo, Fan Qianqian, Han Buxing
College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science & Technology (SUST), Xi'an, 710021, China.
Beijing National Laboratory for Molecular Sciences, Chinese Academy of Sciences (CAS), Beijing, 100190, China.
Adv Sci (Weinh). 2025 Jan;12(4):e2413853. doi: 10.1002/advs.202413853. Epub 2024 Dec 5.
Structural stability of metal-organic framework (MOF) is crucial for their application, and thus it is of great significance to construct MOFs with controllable structural stability. Herein, a strategy based on adjusting the electronic environment of ligands to regulate the structure stability of MOF is proposed. Briefly, a novel Zr-MOF (Zr-TA) with hydroxyl groups is synthesized. The hydroxyl groups are esterified to obtain ester groups with stronger electronegativity, which can weaken the strength of coordination between metal ion and ligand, thereby regulating the structure stability of the Zr-MOF. Notably, this strategy can achieve controllable adjustment of the structure by adding modifiers at the appropriate time. In this work, this strategy is used to greatly improving the binding ability of MOF and collagen fibers, the hydrothermal stability of crosslinked collagen fibers is enhanced by 82.6%. Surprisingly, this strategy can also be applied to other application fields that require dynamic changes in structural stability of MOF. It will open up a new pathway for controlling the structural stability and application performance of MOF.
金属有机框架（MOF）的结构稳定性对其应用至关重要，因此构建具有可控结构稳定性的MOF具有重要意义。在此，提出了一种基于调节配体电子环境来调控MOF结构稳定性的策略。简而言之，合成了一种带有羟基的新型Zr-MOF（Zr-TA）。将羟基酯化以获得具有更强电负性的酯基，这会削弱金属离子与配体之间的配位强度，从而调控Zr-MOF的结构稳定性。值得注意的是，该策略可通过在适当时间添加改性剂来实现结构的可控调节。在这项工作中，此策略用于大幅提高MOF与胶原纤维的结合能力，交联胶原纤维的水热稳定性提高了82.6%。令人惊讶的是，该策略还可应用于其他需要MOF结构稳定性动态变化的应用领域。它将为控制MOF的结构稳定性和应用性能开辟一条新途径。
