Berhuni Mehmet Sait, Yönder Hüseyin, Elkan Hasan, Koyuncu Muhammed Hamza, Özgül Ferhat, Tatlı Faik, Özgönül Abdullah, Uzunköy Ali
General Surgery, Harran University, Şanlıurfa, TUR.
General Surgery, Harran, Şanlıurfa, TUR.
Cureus. 2024 Nov 5;16(11):e73046. doi: 10.7759/cureus.73046. eCollection 2024 Nov.
Systemic immune inflammation index (SII) has been used to evaluate the prognosis of various diseases in recent years. This study aimed to investigate the efficacy of SII in the preoperative diagnosis of complicated acute appendicitis (CAA).
The data of patients who underwent surgery for acute appendicitis (AA) between January 2021 and December 2023 at our clinic were retrospectively analyzed. These patients had undergone surgical operations for AA and had available pathology results. Cases with histopathologic findings of gangrenous appendicitis, phlegmonous appendicitis, perforated appendicitis, and periappendicular abscesses were considered CAA. Cases without these manifestations and reported as appendicitis upon histopathological analysis were considered as noncomplicated acute appendicitis(NCAA). Data recorded and evaluated for the study included age, sex, preoperative C-reactive protein (CRP) levels, white blood cell (WBC) count, neutrophil count, lymphocyte count, platelet count, neutrophil-to-lymphocyte ratio (NLR), Alvarado score (AS), SII, and histopathologic examination results.
A total of 441 patients were included in the study. The mean age of the patients was 34.58 ± 11.70 years. There were 200 women (45.35%) and 241 men (54.65%). The number of noncomplicated and complicated cases was 332 (75.28%) and 109 (24.72%), respectively. SII, AS, NLR, and CRP values were significantly higher in the complicated group (p < 0.001, p < 0.001, p < 0.001, p = 0.001, respectively). The sensitivity and specificity of SII in detecting CAAs were 0.624 and 0.607, respectively, with a cutoff value of 1445.
The sensitivity of SII in detecting CAA was 0.624, with specificity and cutoff values of 0.607 and 1445, respectively. SII can be used as an effective parameter for preoperatively predicting whether an AA case is complicated or not.
近年来，全身免疫炎症指数（SII）已被用于评估各种疾病的预后。本研究旨在探讨SII在复杂急性阑尾炎（CAA）术前诊断中的效能。
回顾性分析2021年1月至2023年12月在我院因急性阑尾炎（AA）接受手术治疗的患者数据。这些患者接受了AA手术且有可用的病理结果。组织病理学检查结果为坏疽性阑尾炎、蜂窝织炎性阑尾炎、穿孔性阑尾炎和阑尾周围脓肿的病例被视为CAA。组织病理学分析未发现这些表现且报告为阑尾炎的病例被视为非复杂性急性阑尾炎（NCAA）。本研究记录和评估的数据包括年龄、性别、术前C反应蛋白（CRP）水平、白细胞（WBC）计数、中性粒细胞计数、淋巴细胞计数、血小板计数、中性粒细胞与淋巴细胞比值（NLR）、阿尔瓦拉多评分（AS）、SII以及组织病理学检查结果。
本研究共纳入441例患者。患者的平均年龄为34.58±11.70岁。其中女性200例（45.35%），男性241例（54.65%）。非复杂性和复杂性病例数分别为332例（75.28%）和109例（24.72%）。复杂性组的SII、AS、NLR和CRP值显著更高（分别为p<0.001、p<0.001、p<0.001、p = 0.001）。SII检测CAA的敏感性和特异性分别为0.624和0.607，临界值为1445。
SII检测CAA的敏感性为0.624，特异性和临界值分别为0.607和1445。SII可作为术前预测AA病例是否复杂的有效参数。
