• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

顶骨骨纤维异常增殖症:一例报告并文献复习

Fibrous Dysplasia of Parietal Bone: A Case Report and Review of Literature.

作者信息

Albushi Shuruq, Almohalwas Maryam, Kushk Fatimah, Alhejaili Rawan, Samman Razan

机构信息

Department of Neurosurgery, King Fahad General Hospital, Medina, SAU.

Department of Neurosurgery, Taibah University, Medina, SAU.

出版信息

Cureus. 2024 Nov 4;16(11):e73023. doi: 10.7759/cureus.73023. eCollection 2024 Nov.

DOI:10.7759/cureus.73023
PMID:39640177
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11618020/
Abstract

Fibrous dysplasia (FD) is a rare, benign, and slowly progressive bone disorder that affects one or more bones, where the normal bone is replaced by atypical fibrous connective tissue, making the bone weak, fragile, and more susceptible to fracture. FD can affect a single bone (monostotic FD) or multiple bones (polyostotic FD). The clinical manifestations and progression of FD vary from one individual to the other. The diagnosis is based on radiological and histopathological findings; a bone biopsy is the diagnostic test of choice for FD. The management of FD depends on the type and severity of the condition. The modality of management is mainly conservative. However, surgery is offered to preserve the function and prevent complications. Surgery is the ideal treatment that helps in definitive diagnosis, determining disease progression or malignant transformation, removing a compressive lesion, cosmetic surgeries, and failure of non-surgical treatments. We reported a new case of monostotic fibrous dysplasia involving the right partial bone in a 27-year-old male who underwent a successful operative excision of the lesion. The patient clinically improved and was discharged later with instructions for his follow-up. We report this case of monostotic FD as it highlights the importance of considering FD in the differential diagnosis of bone lesions, especially in young patients presenting with bone pain or deformities.

摘要

骨纤维异常增殖症(FD)是一种罕见的、良性的、进展缓慢的骨疾病,可累及一块或多块骨骼,正常骨组织被非典型纤维结缔组织替代,导致骨骼变弱、易碎,更易发生骨折。FD可累及单骨(单骨型FD)或多骨(多骨型FD)。FD的临床表现和进展因人而异。诊断基于影像学和组织病理学检查结果;骨活检是FD的首选诊断检查。FD的治疗取决于病情的类型和严重程度。治疗方式主要是保守治疗。然而,也可进行手术以保留功能并预防并发症。手术是理想的治疗方法,有助于明确诊断、确定疾病进展或恶变、切除压迫性病变、进行美容手术以及非手术治疗失败时使用。我们报告了一例27岁男性单骨型骨纤维异常增殖症累及右侧部分骨骼的新病例,该患者成功接受了病变的手术切除。患者临床症状改善,随后出院并得到随访指导。我们报告这例单骨型FD病例,因为它凸显了在骨病变鉴别诊断中考虑FD的重要性,尤其是在出现骨痛或畸形的年轻患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd7/11618020/3351a671a5c8/cureus-0016-00000073023-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd7/11618020/3351a671a5c8/cureus-0016-00000073023-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd7/11618020/3351a671a5c8/cureus-0016-00000073023-i02.jpg

相似文献

1
Fibrous Dysplasia of Parietal Bone: A Case Report and Review of Literature.顶骨骨纤维异常增殖症:一例报告并文献复习
Cureus. 2024 Nov 4;16(11):e73023. doi: 10.7759/cureus.73023. eCollection 2024 Nov.
2
Fibrous dysplasia of the palate: report of a case and review of palatal swellings.腭部纤维性发育异常:1例报告及腭部肿胀的文献复习
Case Rep Pediatr. 2012;2012:179853. doi: 10.1155/2012/179853. Epub 2012 Sep 17.
3
Fibrous dysplasia and cherubism.纤维性发育不良和 cherubism( cherubism 可能是一种特定的医学病症名称,可音译为“克-布二氏病”,但在医学领域可能存在更专业的术语,若有特定要求可进一步查阅相关医学资料确定其准确译名 )。
Indian J Plast Surg. 2015 Sep-Dec;48(3):236-48. doi: 10.4103/0970-0358.173101.
4
An unusual case of polyostotic fibrous dysplasia-A case report.一例罕见的多骨型纤维发育不良病例报告
Indian J Dent Res. 2020 Jul-Aug;31(4):640-643. doi: 10.4103/ijdr.IJDR_409_18.
5
Monostotic fibrous dysplasia involving occipital bone: a case report and review of literature.累及枕骨的单骨型骨纤维异常增殖症:一例报告并文献复习
Pan Afr Med J. 2014 Oct 3;19:124. doi: 10.11604/pamj.2014.19.124.5203. eCollection 2014.
6
Fibrous dysplasia of the inferior turbinate.下鼻甲纤维性发育异常
Int J Clin Exp Pathol. 2013;6(3):531-5. Epub 2013 Feb 15.
7
Conservative treatment of Fibrous Dysplasia.骨纤维异常增殖症的保守治疗
Pak J Med Sci. 2019;35(3):873-876. doi: 10.12669/pjms.35.3.14.
8
The surgical management of monostotic fibrous dysplasia of the inferior turbinate.下鼻甲单骨性骨纤维异常增殖症的手术治疗。
J Stomatol Oral Maxillofac Surg. 2020 Sep;121(4):457-459. doi: 10.1016/j.jormas.2019.10.014. Epub 2019 Nov 2.
9
Analysis of Series of Cases of Fibrous Dysplasia of Proximal Femur in Pediatric Population.小儿近端股骨纤维发育不良系列病例分析
J Orthop Case Rep. 2025 Feb;15(2):249-255. doi: 10.13107/jocr.2025.v15.i02.5298.
10
Histological Diversity, Diagnostic Challenges, and Surgical Treatment Strategies of Fibrous Dysplasia of Upper and Mid-Thirds of the Craniomaxillofacial Complex.颅颌面复合体上三分之一和中三分之一纤维发育不良的组织学多样性、诊断挑战及手术治疗策略
Ann Maxillofac Surg. 2019 Jul-Dec;9(2):289-314. doi: 10.4103/ams.ams_219_19.

引用本文的文献

1
Surgical Management of a Case of Frontoparietal Fibrous Dysplasia.一例额顶叶骨纤维异常增殖症的手术治疗
Cureus. 2025 Jul 18;17(7):e88246. doi: 10.7759/cureus.88246. eCollection 2025 Jul.

本文引用的文献

1
Craniofacial Fibrous Dysplasia: Clinical and Therapeutic Implications.颅面骨纤维结构不良:临床与治疗学意义。
Curr Osteoporos Rep. 2023 Apr;21(2):147-153. doi: 10.1007/s11914-023-00779-6. Epub 2023 Feb 28.
2
Frontal bone fibrous dysplasia in a 6-months-old boy: A distinctive entity.一名6个月大男婴的额骨纤维发育不良:一种独特的病症。
Pediatr Med Chir. 2021 Mar 19;43(1). doi: 10.4081/pmc.2021.225.
3
Fibrous dysplasia of occipital and temporal bone. A case report.枕颞骨纤维发育不良。病例报告。
Oxf Med Case Reports. 2019 May 31;2019(5):omz039. doi: 10.1093/omcr/omz039. eCollection 2019 May.
4
Benign tumours of the bone: A review.骨良性肿瘤:综述。
J Bone Oncol. 2015 Mar 2;4(2):37-41. doi: 10.1016/j.jbo.2015.02.001. eCollection 2015 Jun.
5
Fibrous dysplasia of the inferior turbinate.下鼻甲纤维性发育异常
Int J Clin Exp Pathol. 2013;6(3):531-5. Epub 2013 Feb 15.
6
Clinicoradiologic perspective of a severe case of polyostotic fibrous dysplasia.一例严重多骨型纤维发育不良的临床放射学视角
J Oral Maxillofac Pathol. 2012 May;16(2):301-5. doi: 10.4103/0973-029X.99097.
7
Benign fibro-osseous lesions of the craniofacial complex. A review.颅面复合体的良性纤维-骨病变。综述。
Head Neck Pathol. 2008 Sep;2(3):177-202. doi: 10.1007/s12105-008-0057-2. Epub 2008 May 13.
8
Fibrous dysplasia.纤维性发育不良
J Am Acad Orthop Surg. 2004 Sep-Oct;12(5):305-13. doi: 10.5435/00124635-200409000-00005.
9
Computed tomography of fibrous dysplasia.骨纤维发育不良的计算机断层扫描
Dentomaxillofac Radiol. 2004 Mar;33(2):114-8. doi: 10.1259/dmfr/30164354.
10
Fibrous dysplasia of the temporal bone.
Laryngoscope. 1959 May;69(5):571-4. doi: 10.1288/00005537-195905000-00009.