Albushi Shuruq, Almohalwas Maryam, Kushk Fatimah, Alhejaili Rawan, Samman Razan
Department of Neurosurgery, King Fahad General Hospital, Medina, SAU.
Department of Neurosurgery, Taibah University, Medina, SAU.
Cureus. 2024 Nov 4;16(11):e73023. doi: 10.7759/cureus.73023. eCollection 2024 Nov.
Fibrous dysplasia (FD) is a rare, benign, and slowly progressive bone disorder that affects one or more bones, where the normal bone is replaced by atypical fibrous connective tissue, making the bone weak, fragile, and more susceptible to fracture. FD can affect a single bone (monostotic FD) or multiple bones (polyostotic FD). The clinical manifestations and progression of FD vary from one individual to the other. The diagnosis is based on radiological and histopathological findings; a bone biopsy is the diagnostic test of choice for FD. The management of FD depends on the type and severity of the condition. The modality of management is mainly conservative. However, surgery is offered to preserve the function and prevent complications. Surgery is the ideal treatment that helps in definitive diagnosis, determining disease progression or malignant transformation, removing a compressive lesion, cosmetic surgeries, and failure of non-surgical treatments. We reported a new case of monostotic fibrous dysplasia involving the right partial bone in a 27-year-old male who underwent a successful operative excision of the lesion. The patient clinically improved and was discharged later with instructions for his follow-up. We report this case of monostotic FD as it highlights the importance of considering FD in the differential diagnosis of bone lesions, especially in young patients presenting with bone pain or deformities.
骨纤维异常增殖症(FD)是一种罕见的、良性的、进展缓慢的骨疾病,可累及一块或多块骨骼,正常骨组织被非典型纤维结缔组织替代,导致骨骼变弱、易碎,更易发生骨折。FD可累及单骨(单骨型FD)或多骨(多骨型FD)。FD的临床表现和进展因人而异。诊断基于影像学和组织病理学检查结果;骨活检是FD的首选诊断检查。FD的治疗取决于病情的类型和严重程度。治疗方式主要是保守治疗。然而,也可进行手术以保留功能并预防并发症。手术是理想的治疗方法,有助于明确诊断、确定疾病进展或恶变、切除压迫性病变、进行美容手术以及非手术治疗失败时使用。我们报告了一例27岁男性单骨型骨纤维异常增殖症累及右侧部分骨骼的新病例,该患者成功接受了病变的手术切除。患者临床症状改善,随后出院并得到随访指导。我们报告这例单骨型FD病例,因为它凸显了在骨病变鉴别诊断中考虑FD的重要性,尤其是在出现骨痛或畸形的年轻患者中。