Nezhadi Javad, Fadaee Manouchehr, Ahmadi Somayeh, Kafil Hossein Samadi
Student Research Committee, Tabriz University of Medical Science, Tabriz, Iran.
Department of Microbiology, Faculty of Medicine, Tabriz University of Medical Science, Tabriz, Iran.
Heliyon. 2024 Oct 11;10(20):e39047. doi: 10.1016/j.heliyon.2024.e39047. eCollection 2024 Oct 30.
Microbiota refers to a collection of living microorganisms, including bacteria, yeasts, and viruses, that coexist in various sites of the human body. Microbiota can perform multiple functions in the body, which have an essential effect on human health and homeostasis. For example, the microbiota can digest polysaccharides, produce vitamins, modulate the immune system, and protect the body against pathogens. Various factors can occasionally alter the microbiota population in the human body, a condition known as dysbiosis. Dysbiosis can disrupt the homeostasis of a person's body and cause disease. Recent years have witnessed efforts to restore the microbiota population of an individual's body to its original state and eradicate dysbiosis through microbiota transplantation. The noteworthy point is that different methods such as fecal microbiota transplantation, vaginal microbiota transplantation (VMT), skin microbiota transplantation (SMT), oral microbiota transplantation (OMT), washed microbiota transplantation (WMT), and sinonasal microbiota transplantation (SiMT) are used for microbiota transplantation (MT). According to the results of studies and the usefulness of MT in improving a person's health, the purpose of this study is to investigate different methods of MT to eliminate dysbiosis.
微生物群是指存在于人体各个部位的多种活微生物的集合，包括细菌、酵母和病毒。微生物群在体内可发挥多种功能，对人体健康和体内平衡至关重要。例如，微生物群可消化多糖、产生维生素、调节免疫系统并保护身体免受病原体侵害。多种因素偶尔会改变人体内的微生物群数量，这种情况称为生态失调。生态失调会破坏人体的体内平衡并引发疾病。近年来，人们致力于通过微生物群移植将个体体内的微生物群数量恢复到原始状态并消除生态失调。值得注意的是，微生物群移植（MT）采用了多种不同方法，如粪便微生物群移植、阴道微生物群移植（VMT）、皮肤微生物群移植（SMT）、口腔微生物群移植（OMT）、清洗微生物群移植（WMT）和鼻旁窦微生物群移植（SiMT）。根据研究结果以及MT对改善人体健康的有效性，本研究旨在探讨消除生态失调的不同MT方法。
