Khan Olin, Chandra Das Shohag, Bedoura Sultana
Department of Wet Process Engineering, Bangladesh University of Textiles, Dhaka, Bangladesh.
Department of Dyes and Chemical Engineering, Bangladesh University of Textiles, Dhaka, Bangladesh.
Heliyon. 2024 Oct 9;10(20):e39163. doi: 10.1016/j.heliyon.2024.e39163. eCollection 2024 Oct 30.
The innovative utilization of the microencapsulation technique and the antimicrobial properties of (A.I.) and (T.C.) present a novel approach to producing antiseptic wipes. In this study, microcapsules with A.I. oil and T.C. extracts were synthesized and integrated into non-woven cotton fabric aiming to create disposable antiseptic medical wipes. The T.C. extract and A.I. oil were used in a 1:1 ratio and microencapsulated utilizing sodium alginate as the encapsulation material through an ionic gelation process. The optical microscope analysis of microcapsules revealed diverse microcapsule sizes, ranging from 50 μm to 180 μm in diameter and scanning electron microscopy revealed that the treated fabric has uniform distribution of microcapsules across the entire fabric surface. The antimicrobial efficacy was evaluated through disk diffusion for the extract and oil and the fabric's antimicrobial activity was assessed by measuring bacterial reduction. The treated fabric displayed substantial reductions in both Gram-positive bacteria ( (87 %) and (99 %)) and Gram-negative bacteria ( (81 %) and (99 %)). Although the treated fabric exhibited a slight decrease in whiteness (48.5-39), this alteration did not adversely affect other fabric properties. These findings underscore the potential of microencapsulated natural extracts in producing effective antimicrobial medical wipes, thereby contributing to infection control.
微胶囊技术的创新应用以及（A.I.）和（T.C.）的抗菌特性为生产抗菌湿巾提供了一种新方法。在本研究中，合成了含有A.I.油和T.C.提取物的微胶囊，并将其整合到无纺布中，旨在制造一次性抗菌医用湿巾。T.C.提取物和A.I.油以1:1的比例使用，并通过离子凝胶化过程利用海藻酸钠作为包封材料进行微胶囊化。微胶囊的光学显微镜分析显示微胶囊尺寸各异，直径范围为50μm至180μm，扫描电子显微镜显示处理后的织物在整个织物表面具有微胶囊的均匀分布。通过纸片扩散法评估提取物和油的抗菌效果，并通过测量细菌减少量来评估织物的抗菌活性。处理后的织物在革兰氏阳性菌（（87%）和（99%））和革兰氏阴性菌（（81%）和（99%））方面均有显著减少。尽管处理后的织物白度略有下降（48.5 - 39），但这种变化并未对其他织物性能产生不利影响。这些发现强调了微胶囊化天然提取物在生产有效的抗菌医用湿巾方面的潜力，从而有助于感染控制。
