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孕期及产后中风的可预防性

Preventability of stroke during pregnancy and postpartum.

作者信息

Ding Jia Jennifer, Mitta Srilakshmi, Kole-White Martha, Roth Julie, Malhamé Isabelle

机构信息

Department of Obstetrics and Gynecology, Brown/Women and Infants Hospital, Providence, RI, USA.

Department of Obstetric and Consultative Medicine, Brown/Women and Infants Hospital of Rhode Island, Providence, RI, USA.

出版信息

Obstet Med. 2024 Dec;17(4):208-212. doi: 10.1177/1753495X231213437. Epub 2023 Nov 17.

DOI:10.1177/1753495X231213437
PMID:39640951
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11615985/
Abstract

BACKGROUND

The preventability of strokes during pregnancy and postpartum is understudied.

METHODS

We identified patients with ischemic and hemorrhagic strokes in pregnancy or within 12 weeks postpartum between 2009 and 2020 at an obstetric teaching hospital. We described the clinical course of the included cases. A multi-disciplinary panel adjudicated each occurrence of stroke according to a modified classification system for preventability.

RESULTS

Fifteen patients experienced a stroke during pregnancy or postpartum. Precisely, 60% presented with a headache, and 47% of events were complicated by severe obstetrical hypertension. Two cases were thought to be "possibly preventable" due to delays in presentation to care and miscommunication regarding hypertension management goals.

CONCLUSION

In a cohort of pregnant and postpartum patients with stroke at a tertiary-care center, strokes may be prevented by future initiatives focusing on patient and provider education regarding early warning signs of pregnancy-associated stroke and hypertension thresholds and management specific to pregnancy.

摘要

背景

孕期和产后中风的可预防性研究不足。

方法

我们在一家产科教学医院中,识别出2009年至2020年期间孕期或产后12周内发生缺血性和出血性中风的患者。我们描述了纳入病例的临床病程。一个多学科小组根据改良的可预防性分类系统对每一次中风事件进行判定。

结果

15名患者在孕期或产后发生了中风。确切地说,60%的患者出现头痛,47%的事件并发严重产科高血压。由于就诊延迟以及高血压管理目标方面的沟通失误,有2例被认为“可能可预防”。

结论

在一家三级医疗中心的孕期和产后中风患者队列中,未来通过针对患者和医护人员开展关于妊娠相关中风早期预警信号、高血压阈值以及孕期特定管理的教育举措,中风可能得以预防。

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本文引用的文献

1
Cardiovascular Severe Maternal Morbidity and Mortality at Delivery in the United States: A Population-Based Study.美国分娩时心血管疾病导致的严重孕产妇发病和死亡:一项基于人群的研究。
JACC Adv. 2022 Oct 20;1(4):100121. doi: 10.1016/j.jacadv.2022.100121. eCollection 2022 Oct.
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Risk of Stroke in Migrainous Women, a Hidden Association: A Systematic Review.偏头痛女性的中风风险:一种隐藏的关联——系统评价
Cureus. 2022 Jul 21;14(7):e27103. doi: 10.7759/cureus.27103. eCollection 2022 Jul.
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Implementation of a universal postpartum blood pressure monitoring program: feasibility and outcomes.实施一项通用的产后血压监测计划:可行性与结果
Am J Obstet Gynecol MFM. 2022 May;4(3):100613. doi: 10.1016/j.ajogmf.2022.100613. Epub 2022 Mar 10.
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Sociodemographic Disparities in Utilization of Childbirth Education.分娩教育利用方面的社会人口学差异
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Maternal Stroke Associated With Pregnancy.母体脑卒中与妊娠相关。
Continuum (Minneap Minn). 2022 Feb 1;28(1):93-121. doi: 10.1212/CON.0000000000001078.
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Birth Volume and Geographic Distribution of US Hospitals With Obstetric Services From 2010 to 2018.2010 年至 2018 年美国具有产科服务的医院的分娩量和地理分布。
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Am J Obstet Gynecol. 2021 Sep;225(3):329.e1-329.e10. doi: 10.1016/j.ajog.2021.05.012. Epub 2021 May 20.
8
Initiatives to Reduce Maternal Mortality and Severe Maternal Morbidity in the United States : A Narrative Review.美国降低孕产妇死亡率和严重孕产妇发病率的举措:一项叙述性综述
Ann Intern Med. 2020 Dec 1;173(11 Suppl):S3-S10. doi: 10.7326/M19-3258.
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Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin Summary, Number 222.妊娠期高血压与子痫前期:ACOG 实践通报摘要,第 222 号。
Obstet Gynecol. 2020 Jun;135(6):1492-1495. doi: 10.1097/AOG.0000000000003892.
10
Preventing Complications in Pregnant Women With Cardiac Disease.预防患有心脏病的孕妇出现并发症。
J Am Coll Cardiol. 2020 Mar 31;75(12):1443-1452. doi: 10.1016/j.jacc.2020.01.039.