McStay Daniel, McBride Sandy, Hill Sharleen, Sutton Jonathan, Saleem Amber, Singh Vinita
Department of Obstetrics & Gynaecology, Royal Free London NHS Foundation Trust, London, UK.
Department of Dermatology, Royal Free London NHS Foundation Trust, London, UK.
Obstet Med. 2024 Dec;17(4):236-239. doi: 10.1177/1753495X221149134. Epub 2023 Jan 10.
Generalised pustular psoriasis of pregnancy (GPPP) is a rare dermatosis that presents in the third trimester. It merits careful clinical assessment given the difficulty in diagnosis, impact on maternal health and association with placental insufficiency. We present a case of generalised pustulosis in a pregnant woman at 30 weeks' gestation and describe the clinico-pathological challenges in obtaining a diagnosis of GPPP. Furthermore, we provide evidence from cardiotocography and ultrasound of evolving fetal compromise and describe how intensive management can facilitate a positive maternal-fetal outcome.
妊娠泛发性脓疱型银屑病(GPPP)是一种罕见的皮肤病,多在妊娠晚期出现。鉴于其诊断困难、对母体健康的影响以及与胎盘功能不全的关联,需要进行仔细的临床评估。我们报告一例妊娠30周孕妇的泛发性脓疱病病例,并描述在诊断GPPP时所面临的临床病理挑战。此外,我们提供了胎心监护和超声检查显示胎儿逐渐出现窘迫的证据,并描述了强化治疗如何促进母婴获得良好结局。