Huang Ya-Lin A, Lowy Elliott, Zhu Weiming, Yu Lei, Wei Wei, Maier Marissa M, Hoover Karen W, Beste Lauren A
Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
VA Puget Sound Health Care System, Seattle, WA.
J Acquir Immune Defic Syndr. 2025 Jan 1;98(1):8-11. doi: 10.1097/QAI.0000000000003532.
It is important to monitor national HIV preexposure prophylaxis (PrEP) use in the United States. However, PrEP use data in the Veterans Health Administration (VHA) system are not included in the current monitoring surveillance. To address this gap, we examined the trends in PrEP use among U.S. Veterans receiving health services in the VHA system.
We analyzed 2014-2022 VHA data to identify the annual number and prevalence of persons aged ≥18 years prescribed PrEP, stratified by sex, age, race/ethnicity, and region. We also assessed trends by calculating the estimated annual percent change and 95% confidence intervals using Poisson models.
The number of Veterans prescribed PrEP increased from 361 in 2014 to 6050 in 2022 with an estimated annual percent change of 29.6% (95% CI: 22.6 to 37.1). Of 6050 Veterans with PrEP prescriptions in 2022, 95.2% were men, 4.8% were women, 50.4% were White, 24.5% Black or African American (Black), and 14.0% Hispanic or Latino. The prevalence of Black and Hispanic or Latino individuals prescribed PrEP increased significantly from 2014 to 2022.
VHA data fill a gap in monitoring PrEP use in the United States. We observed an increasing trend in the number of Veterans prescribed PrEP similar to trends among persons with commercial or public health insurance.
监测美国全国范围内的艾滋病病毒暴露前预防（PrEP）使用情况很重要。然而，退伍军人健康管理局（VHA）系统中的PrEP使用数据并未纳入当前的监测调查中。为了填补这一空白，我们研究了在VHA系统中接受医疗服务的美国退伍军人中PrEP使用的趋势。
我们分析了2014 - 2022年的VHA数据，以确定按性别、年龄、种族/族裔和地区分层的18岁及以上开具PrEP处方的人数和患病率。我们还通过使用泊松模型计算估计的年度百分比变化和95%置信区间来评估趋势。
开具PrEP处方的退伍军人数量从2014年的361人增加到2022年的6050人，估计年度百分比变化为29.6%（95%CI：22.6至37.1）。在2022年开具PrEP处方的6050名退伍军人中，95.2%为男性，4.8%为女性，50.4%为白人，24.5%为黑人或非裔美国人（黑人），14.0%为西班牙裔或拉丁裔。从2014年到2022年，开具PrEP处方的黑人和西班牙裔或拉丁裔个体的患病率显著增加。
VHA数据填补了美国PrEP使用监测的空白。我们观察到开具PrEP处方的退伍军人数量呈上升趋势，这与拥有商业或公共医疗保险的人群趋势相似。
