Hata Yuuki, Serizawa Takeshi
Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Institute of Science Tokyo, 2-12-1-H-121 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
Adv Colloid Interface Sci. 2025 Feb;336:103361. doi: 10.1016/j.cis.2024.103361. Epub 2024 Nov 29.
Colloidal cellulose nanoparticles, or nanocelluloses, are derived from natural cellulose sources in a top-down manner via physical and/or chemical treatments that extract naturally occurring cellulose nanostructures. Naturally derived nanocelluloses have been successfully commercialized in various fields, and their potential is still being widely explored in materials science. Moreover, recent advances in nanoarchitectonics of low-molecular-weight cellulose, or cello-oligosaccharides, have opened new avenues for developing "artificial nanocelluloses". Artificial nanocelluloses composed of cello-oligosaccharides synthesized via enzymatic oligomerization or solid-phase glycan synthesis technology are termed "synthetic nanocelluloses". These nanostructures are abiotically constructed in a bottom-up manner at the molecular level via self-assembly of cello-oligosaccharides in vitro. Modulation of the assembly process and molecular design provides control over the molecular alignment, nanomorphology, and surface functionality of artificial nanocelluloses. This review summarizes recent research progress in artificial nanocelluloses, from the preparation and self-assembly of cello-oligosaccharides to their potential applications.
胶体纤维素纳米颗粒，即纳米纤维素，是通过物理和/或化学处理以自上而下的方式从天然纤维素来源中提取天然存在的纤维素纳米结构而得到的。天然衍生的纳米纤维素已在各个领域成功实现商业化，并且其潜力仍在材料科学中得到广泛探索。此外，低分子量纤维素（即低聚纤维素）的纳米结构构建技术的最新进展为开发“人工纳米纤维素”开辟了新途径。通过酶促寡聚化或固相聚糖合成技术合成的由低聚纤维素组成的人工纳米纤维素被称为“合成纳米纤维素”。这些纳米结构是通过低聚纤维素在体外的自组装在分子水平上以自下而上的方式非生物构建的。组装过程的调控和分子设计可控制人工纳米纤维素的分子排列、纳米形态和表面功能。本文综述了人工纳米纤维素的最新研究进展，从低聚纤维素的制备和自组装到其潜在应用。
