Song Qingyuan, Shan Xueling, Jiang Ding, Wang Wenchang, Dai Guohong
Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou, 213164, Jiangsu, China; School of Safety Science and Engineering, Changzhou University, Changzhou, 213164, Jiangsu, China.
Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou, 213164, Jiangsu, China.
Anal Chim Acta. 2025 Jan 15;1335:343416. doi: 10.1016/j.aca.2024.343416. Epub 2024 Nov 20.
The potential hazards of bisphenol A (BPA) to the environment have become a global concern. Herein, 2D Zn-based metal-organic framework nanosheet (2D Zn-MOF) and MnCO nanocomposite (Zn-MOF-MnCO), an efficient electrochemiluminescence (ECL) probe was first synthesized and constructed for trace detection of BPA. Owing to the elimination of the aggregation-induced quenching (ACQ) effect of polycyclic aromatic hydrocarbons (PAHs), the leaf-like Zn-MOF exhibited a satisfactory ECL signal. The MnCO, which has excellent biocompatibility, showed excellent ECL efficiency in the presence of KSO. With the covalent binding of Zn-MOF and MnCO, we demonstrated that the ECL intensity and stability of Zn-MOF-MnCO improved significantly. In addition, the inner filter effect (IFE) of FeO-NH NPs toward Zn-MOF-MnCO had been confirmed to be the ECL quenching mechanism. Based on above strategies, the proposed ECL-IFE biosensor exhibited a trace detection ability of BPA in a wide linear range (10 fM ∼ 10 μM) with a low detection limit (4.2 fM). Further in-depth study confirmed the excellent repeatability, selectivity, and stability of sensors, which provided a fresh sensing platform for trace detection of BPA in the environment.
