Arad I, Glick B, Dgani Y, Salpeter L, Eyal F
Am J Perinatol. 1986 Apr;3(2):104-6. doi: 10.1055/s-2007-999843.
Forty-two pairs of maternal and cord plasma vitamin C levels were determined after term, preterm, and multiple gestation pregnancies and 95 determinations of plasma ascorbate were performed on 36 premature infants who were fed a recommended infant formula throughout the first month of life. There were no significant changes of the cord or maternal ascorbate levels or of the cord/maternal ascorbate ratio between term, preterm, and multiple gestation cases. A significant negative correlation was found between the maternal ascorbate levels and the cord/maternal ascorbate ratio, supporting previous observations that high fetal blood levels of vitamin C are maintained even in cases where the maternal vitamin nutrition is poor. A rapid decline from cord levels was evident during the first week of life, followed by maintenance of relatively low plasma ascorbate levels, despite supplementation of recommended vitamin nutrition. Further monitoring of ascorbate levels in premature infants is suggested for better adjustment of the recommendations for vitamin C supplementation.
测定了足月、早产和多胎妊娠后的42对母婴血浆维生素C水平，并对36名在出生后第一个月全程喂养推荐婴儿配方奶粉的早产儿进行了95次血浆抗坏血酸测定。足月、早产和多胎妊娠病例之间，脐带血或母体抗坏血酸水平以及脐带血/母体抗坏血酸比值均无显著变化。母体抗坏血酸水平与脐带血/母体抗坏血酸比值之间存在显著负相关，这支持了之前的观察结果，即即使在母体维生素营养较差的情况下，胎儿血液中高维生素C水平仍能维持。出生后第一周，血浆抗坏血酸水平明显从脐带血水平迅速下降，尽管补充了推荐的维生素营养，但随后血浆抗坏血酸水平维持在相对较低水平。建议进一步监测早产儿的抗坏血酸水平，以便更好地调整维生素C补充建议。
