Meldrum-Hanna W, Cartmill T, Johnson D, Celermajer J, Hawker R
Br Heart J. 1986 Apr;55(4):371-5. doi: 10.1136/hrt.55.4.371.
Between 1971 and December 1976, 27 children with congenital heart disease underwent right ventricular outflow tract reconstruction with conduits incorporating a Björk-Shiley valve. The conditions corrected were pulmonary atresia with ventricular septal defect (14 patients), truncus arteriosus (6 patients), and complex disease (7 patients). At operation the children were aged from 12 days to 16 years (five patients were less than one year old). Overall mortality for the group was high (52%). There were nine early deaths and five late ones. Actuarial survival till death or reoperation was 55% at four years, 35% at eight years, and 28% at 12 years. Ten children subsequently underwent reoperation for conduit stenosis caused by neointimal proliferation and valve obstruction. The new conduits incorporated a biological valve. Mortality was highest in patients aged less than one year, and in those with truncus arteriosus, severe pulmonary hypertension, or complex heart disease. Mechanical valves should be avoided in conduit reconstruction of the right ventricular outflow tract for congenital heart disease.
1971年至1976年12月期间,27例先天性心脏病患儿接受了采用包含 Björk-Shiley 瓣膜的管道进行的右心室流出道重建手术。矫正的病症包括室间隔缺损合并肺动脉闭锁(14例患者)、永存动脉干(6例患者)和复杂疾病(7例患者)。手术时患儿年龄从12天至16岁不等(5例患者小于1岁)。该组患者的总体死亡率较高(52%)。有9例早期死亡和5例晚期死亡。至死亡或再次手术的精算生存率在4年时为55%,8年时为35%,12年时为28%。10例患儿随后因新内膜增生导致的管道狭窄和瓣膜梗阻而接受了再次手术。新管道采用了生物瓣膜。年龄小于1岁的患者、患有永存动脉干、重度肺动脉高压或复杂心脏病的患者死亡率最高。在先天性心脏病右心室流出道的管道重建中应避免使用机械瓣膜。