Hannoun-Levi J M, Savignoni A, Lemonnier J, Kirova Youlia
Department of Radiation Oncology, Antoine Lacassagne Cancer Centre, University Cote d'Azur, Nice, France.
Department of Bio Statistics, Institute Curie, Paris, France.
Radiother Oncol. 2025 Feb;203:110659. doi: 10.1016/j.radonc.2024.110659. Epub 2024 Dec 5.
Results from prospective randomized trial results are required to provide practice-changing level-1 evidence. However, if such a trial is not feasible, we should not accept that consequently practice could not change. We discuss hereby a pragmatically approach based on methodological alternatives.
前瞻性随机试验结果是提供能改变临床实践的一级证据所必需的。然而，如果这样的试验不可行，我们不应因此就认为临床实践无法改变。在此，我们讨论一种基于方法学替代方案的实用方法。
