Górny M K, Jezewska E, Krzyśko R, Stawarz M, Zeromski J
Neoplasma. 1979;26(6):729-36.
By means of indirect immunofluorescence a number of primary lung cancer patient sera and control sera were tested for anti-tumor antibody activity on living tumor cells as a substrate. Antibodies against surface antigens were the most frequently detected in autologous system (in 65%) on cells derived from fresh surgical material of lung cancer. They were also found in 50% of cases using tumor cells from primary short-term culture. When established cell line of lung cancer was used (E-14) in allogeneic system, the antibodies were detected in only 22% of examined lung cancer sera. Absorption of positive sera with homogenates of normal tissues did not abolish their specific activity. Positive reactions were confined to squamous cell type of bronchogenic carcinoma.
通过间接免疫荧光法，以活肿瘤细胞为底物，检测了一些原发性肺癌患者血清和对照血清的抗肿瘤抗体活性。在自体系统中（65%），针对肺癌新鲜手术材料来源细胞表面抗原的抗体最为常见。在50%的病例中，使用原发性短期培养的肿瘤细胞时也发现了此类抗体。当在同种异体系统中使用肺癌细胞系（E-14）时，在所检测的肺癌血清中仅22%检测到抗体。用正常组织匀浆吸收阳性血清并没有消除其特异性活性。阳性反应仅限于支气管源性鳞状细胞癌。
