超越简单的因果关系：探索产前暴露于阿片类药物和其他物质的儿童的长期结局。
Beyond a simple cause and effect relationship: Exploring the long-term outcomes of children prenatally exposed to opioids and other substances.
作者信息
Burduli Ekaterina, Jones Hendrée E
机构信息
Washington State University, College of Nursing, Spokane, WA, USA; Washington State University, Department of Community and Behavioral Health, Elson S. Floyd College of Medicine, Spokane, WA, USA.
University of North Carolina at Chapel Hill, UNC Horizons, Department of Obstetrics and Gynecology, Chapel Hill, NC, USA.
出版信息
Semin Perinatol. 2025 Feb;49(1):152010. doi: 10.1016/j.semperi.2024.152010. Epub 2024 Dec 7.
The long-term outcomes of children exposed to opioids and other substances in utero, specifically those diagnosed with Neonatal Abstinence Syndrome (NAS), present a complex interaction of different factors. First, NAS and its clinical presentation will be defined, then summarized will be an overview of NAS prevalence, recent trends, and significance of NAS in the context of the rising synthetic opioid and polysubstance use. Highlighted will also be the identified risk factors for NAS, especially regarding the role of environmental and psychosocial stressors during pregnancy. Finally, reviewed will be the existing NAS literature, including its gaps and limitations, and suggested recommendations for future research and policy considerations for improving care for children and families impacted by NAS.
子宫内接触阿片类药物和其他物质的儿童的长期结局，特别是那些被诊断为新生儿戒断综合征（NAS）的儿童，呈现出不同因素的复杂相互作用。首先，将对NAS及其临床表现进行定义，然后概述NAS的患病率、近期趋势以及在合成阿片类药物和多物质使用增加背景下NAS的重要性。还将强调已确定的NAS风险因素，特别是孕期环境和心理社会压力源的作用。最后，将回顾现有的NAS文献，包括其差距和局限性，并提出未来研究建议以及改善受NAS影响的儿童和家庭护理的政策考量。
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