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本文引用的文献

1
A Prospective Randomised Comparative Four-arm Intervention Study of Efficacy and Safety of Saroglitazar and Vitamin E in Patients With Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH)-SVIN TRIAL.一项关于沙罗格列他与维生素E治疗非酒精性脂肪性肝病(NAFLD)/非酒精性脂肪性肝炎(NASH)疗效和安全性的前瞻性随机对照四臂干预研究——SVIN试验
J Clin Exp Hepatol. 2024 Sep-Oct;14(5):101398. doi: 10.1016/j.jceh.2024.101398. Epub 2024 Mar 18.
2
A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.一项评估 Resmetirom 治疗伴有肝纤维化的 NASH 的 3 期随机对照试验。
N Engl J Med. 2024 Feb 8;390(6):497-509. doi: 10.1056/NEJMoa2309000.
3
Efficacy and safety of saroglitazar in real-world patients of non-alcoholic fatty liver disease with or without diabetes including compensated cirrhosis: A tertiary care center experience.沙罗格列扎在合并或不合并糖尿病(包括代偿期肝硬化)的非酒精性脂肪性肝病真实世界患者中的疗效和安全性:一家三级医疗中心的经验
JGH Open. 2023 Feb 20;7(3):215-220. doi: 10.1002/jgh3.12878. eCollection 2023 Mar.
4
Indian National Association for Study of the Liver (INASL) Guidance Paper on Nomenclature, Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease (NAFLD).印度国家肝脏研究协会(INASL)关于非酒精性脂肪性肝病(NAFLD)命名、诊断和治疗的指导文件。
J Clin Exp Hepatol. 2023 Mar-Apr;13(2):273-302. doi: 10.1016/j.jceh.2022.11.014. Epub 2022 Dec 7.
5
Saroglitazar for Nonalcoholic Fatty Liver Disease: A Single Centre Experience in 91 Patients.司美格鲁肽治疗非酒精性脂肪性肝病:91例患者的单中心经验
J Clin Exp Hepatol. 2022 Mar-Apr;12(2):435-439. doi: 10.1016/j.jceh.2021.06.015. Epub 2021 Jun 19.
6
Safety and Efficacy of Saroglitazar in Nonalcoholic Fatty Liver Patients With Diabetic Dyslipidemia-A Prospective, Interventional, Pilot Study.沙罗格列扎用于合并糖尿病血脂异常的非酒精性脂肪肝患者的安全性和有效性——一项前瞻性、干预性、试点研究
J Clin Exp Hepatol. 2022 Jan-Feb;12(1):61-67. doi: 10.1016/j.jceh.2021.03.012. Epub 2021 Apr 9.
7
Saroglitazar, a PPAR-α/γ Agonist, for Treatment of NAFLD: A Randomized Controlled Double-Blind Phase 2 Trial.沙格列汀,一种 PPAR-α/γ 激动剂,用于治疗非酒精性脂肪性肝病:一项随机对照、双盲 2 期试验。
Hepatology. 2021 Oct;74(4):1809-1824. doi: 10.1002/hep.31843. Epub 2021 Jul 19.
8
Saroglitazar in patients with non-alcoholic fatty liver disease and diabetic dyslipidemia: a prospective, observational, real world study.非酒精性脂肪性肝病合并糖尿病血脂异常患者应用沙格列汀:一项前瞻性、观察性、真实世界研究。
Sci Rep. 2020 Dec 3;10(1):21117. doi: 10.1038/s41598-020-78342-x.
9
A Phase 2 Double Blinded, Randomized Controlled Trial of Saroglitazar in Patients With Nonalcoholic Steatohepatitis.一项沙格列汀治疗非酒精性脂肪性肝炎患者的 2 期双盲、随机对照临床试验。
Clin Gastroenterol Hepatol. 2021 Dec;19(12):2670-2672. doi: 10.1016/j.cgh.2020.10.051. Epub 2020 Nov 2.
10
An Observational Study of Reduction in Glycemic Parameters and Liver Stiffness by Saroglitazar 4 mg in Patients With Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease.一项关于4毫克沙罗格列扎对2型糖尿病合并非酒精性脂肪性肝病患者血糖参数及肝脏硬度降低作用的观察性研究。
Cureus. 2020 Jul 8;12(7):e9065. doi: 10.7759/cureus.9065.

The SVIN-Trial-Just Another Brick in the Wall?

作者信息

Mehtani Rohit

机构信息

Department of Hepatology, Amrita Institute of Medical Sciences and Research Centre, Faridabad, Haryana, India.

出版信息

J Clin Exp Hepatol. 2025 Mar-Apr;15(2):102449. doi: 10.1016/j.jceh.2024.102449. Epub 2024 Oct 30.

DOI:10.1016/j.jceh.2024.102449
PMID:39649151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11617671/
Abstract
摘要