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Association between gastroesophageal reflux disease and metabolic syndrome: a bidirectional two-sample Mendelian randomization analysis.

作者信息

He Tao, Geng Xiaoling, Lin Xue, Li Yufei, Duan Zhijun

机构信息

Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Department of Digestive Endoscopy, Central Hospital of Dalian University of Technology, Dalian, Dalian, China.

出版信息

Arch Med Sci. 2024 Oct 22;20(5):1715-1719. doi: 10.5114/aoms/193708. eCollection 2024.

DOI:10.5114/aoms/193708
PMID:39649271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11623159/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13c5/11623159/9b911efc7fea/AMS-20-5-193708-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13c5/11623159/a90d2798fe70/AMS-20-5-193708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13c5/11623159/9b911efc7fea/AMS-20-5-193708-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13c5/11623159/a90d2798fe70/AMS-20-5-193708-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13c5/11623159/9b911efc7fea/AMS-20-5-193708-g002.jpg

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本文引用的文献

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Association of leptin receptor gene Gln223Arg polymorphism with insulin resistance and hyperglycemia in patients with metabolic syndrome.瘦素受体基因Gln223Arg多态性与代谢综合征患者胰岛素抵抗及高血糖的相关性
Arch Med Sci. 2023 Jul 28;20(1):54-60. doi: 10.5114/aoms/170121. eCollection 2024.
2
Global burden and epidemic trends of gout attributable to high body mass index from 1990 to 2019.1990年至2019年因高体重指数导致的痛风全球负担及流行趋势
Arch Med Sci. 2024 Jan 18;20(1):71-80. doi: 10.5114/aoms/175469. eCollection 2024.
3
Metabolic syndrome is associated with higher rate of gastroesophageal reflux disease: a meta-analysis.
代谢综合征与胃食管反流病的发生率升高有关：一项荟萃分析。
Neurogastroenterol Motil. 2022 May;34(5):e14234. doi: 10.1111/nmo.14234. Epub 2021 Aug 11.
4
Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis.多特质遗传关联分析确定了 50 个新的胃食管反流风险位点，7 个新的 Barrett 食管位点，并为反流诊断中的临床异质性提供了新的见解。
Gut. 2022 Jun;71(6):1053-1061. doi: 10.1136/gutjnl-2020-323906. Epub 2021 Jun 29.
5
Gastroesophageal Reflux Disease: A Review.胃食管反流病：综述。
JAMA. 2020 Dec 22;324(24):2536-2547. doi: 10.1001/jama.2020.21360.
6
Trends in the Prevalence of Metabolic Syndrome in the United States, 2011-2016.美国代谢综合征流行趋势，2011-2016 年。
JAMA. 2020 Jun 23;323(24):2526-2528. doi: 10.1001/jama.2020.4501.
7
Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.评估循环脂蛋白脂质与载脂蛋白与冠心病风险的关系：多变量孟德尔随机分析。
PLoS Med. 2020 Mar 23;17(3):e1003062. doi: 10.1371/journal.pmed.1003062. eCollection 2020 Mar.
8
Genome-Wide Association Study of the Metabolic Syndrome in UK Biobank.英国生物库代谢综合征的全基因组关联研究。
Metab Syndr Relat Disord. 2019 Dec;17(10):505-511. doi: 10.1089/met.2019.0070. Epub 2019 Oct 7.
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An update on metabolic syndrome: Metabolic risk markers and adipokines in the development of metabolic syndrome.代谢综合征的最新进展：代谢风险标志物与脂肪因子在代谢综合征发展中的作用
Diabetes Metab Syndr. 2019 Jul-Aug;13(4):2409-2417. doi: 10.1016/j.dsx.2019.06.005. Epub 2019 Jun 8.
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Bioinformatics. 2019 Nov 1;35(22):4851-4853. doi: 10.1093/bioinformatics/btz469.